Imagine if you loss control of your body but your mind stayed unaffected. You would be a prisoner in your own body, all leading up to your death sentence. That is the sad fate for the people diagnosed with Amyotrophic lateral sclerosis (ALS). “Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder was first described by Ran in 1850. This description was then expanded in 1873 by Charcot, who emphasized the involvement of the corticospinal tracts. In the United States, ALS is often referred to as Lou Gehrig's disease, after the famous ball player who was stricken by the disease in the midst of his career. (Yale School of Medicine, 2014)” In this paper will go through the ...view middle of the document...
The cause of this disease process is still unknown. (MedicineNet, Inc, 2012)”
In the early stages of ALS the motor neurons begin to because of the ALS, this shuts down the brain function that controls muscle movement. Once this begins muscles may become weak and soft, or stiff and tight, and spastic and atrophy will occur. The physical signs in the early stages may include fatigue, poor balance, slurred speech, tripping. (Muscular Dystrophy Association Inc., 2013)
In the middle stages muscles symptoms spread to whole body. The unused muscles may cause contractures, causing rigid joints which are painful and sometimes deformed. In this stage the muscle weakness starts to progresses to paralysis. Some are paralyzed, while others are muscle are just weakened or not affected at all. It has also been observed some people will also go through episodes of uncontrolled and inappropriate laughing or crying when the person usually doesn’t feel that way. (Muscular Dystrophy Association Inc., 2013)
In the late stage of ALS mobility is extremely limited, most voluntary muscles are paralyzed. Continued loss of the ability to speak, eating or drinking by mouth. This stage also includes poor respiration this happens due to the muscles that help move air in and out of the lungs are affected this has also been the leading cause of death in ALS. This disease also come along with fatigue, unclear thinking, headaches and susceptibility to pneumonia. All of that leading up the persons death. (Muscular Dystrophy Association Inc., 2013).
There are three types of ALS and they each have a different set of risk factors. First off, the most common type of ALS in the United States is called sporadic 90–95% of ALS cases are sporadic and increasing. The second types is called familial ALS (FALS) is about 5-10 % of cases in the united states and Guamanian was a major type in the 1950 and early 1960’s.
Sporadic: The sporadic ALS risk factors are not clear. There is some evidence that points to the immune system. This is because of increased levels of the neurotransmitters glutamate which can overstimulate motor neurons and cause them to die.
Familial: The familial ALS risk factor is an inherited genetic...