One of the great struggles in modern medicine is being able to replace vital organs in patients that are unable to be donated, such as the lower intestines and stomach. There are many obstacles that stand in the way between being able to synthesize or re-create said organs, but simple builds and simple ideas can help scientists to try to overcome the obstacles. Re-creating the human stomach in an artificial setting will help understand the basics in artificial organ replacement.
The first step in creating an artificial stomach is background research. This Research Project will take extensive research to complete. An inexpensive (.99c) program was purchased early into the research project that highlights the digestive system and how it all “fits together.” The application also gives a very good and detailed external view of the stomach and it's connection with the Esophagus.
The second step is the build of schematic 1. This is the first build and will eventually be tested to see if it can meet the following criteria: The build must be able to withstand the acidic conditions and also must be able to break down food to be moved into the lower intestines.
Once the schematic is complete, build one will begin and then tested. After testing has concluded, edits in the schematic will be made and the process will repeat. A “Reflection” Period will begin when a suitable (fits all the criteria) is completed. This reflection period is the stage when conclusions on the builds are made, and where the overall project is reflected upon. What could be improved? How realistic is it?
The materials required for the creation of an artificial human stomach include: Drafting materials that include draft paper and SolidWorks, a 3-D modeling application. SolidWorks is a very expensive application, ranging from $150.00 (student's license) to $4000.00 for a years license. This
application could be especially useful for seeing a rough 3-D draft of the proposed schematic. If ever ventured, the application files from SolidWorks can be printed on a 3-D printer, but the 3-D printed product will be too weak and unsuitable for human use. The material of the product would easily be
destroyed by the stomach acid.
The materials needed for the builds of the drafts include: a variety of cells to coat the walls of the artificial stomach. These cells include but not are not limited to epithelial cells and Parietal cells. Epithelial cells are vital for the stomach because they act like “Bricks.” The cells form layers and folds that leave little intercellular space and coat the stomach in all layers. These cells won't do much in the early placement in the artificial stomach, but over time the cells will anchor and form said layers. Parietal Cells are vital in the stomach because they secrete gastric acid that will aide in the breaking down of food molecules.
Digestive Enzymes may also be purchased to be placed within the stomach, but it is not 100%...