Caffeine Effects In The Brain Essay

1844 words - 7 pages

Caffeine Effects In The Brain

Caffeine acts in a multitude of ways in the brain. The
most recent studies explore the cooperative effects of
adenosine and dopamine, as well as the increase in calcium
in the interstitial fluid and possible accumulation of
cyclic adenosine monophospate. The most popular discussions
of earlier studies of caffeine demonstrate its antagonistic
effects on adenosine receptors. While it has been reported
that adenosine receptors are located throughout the brain,
the various subtypes can be found in very specific areas.
Studies have also shown that caffeine reactions in the brain
are based on the localization of adenosine receptors,
dopamine receptors, and the amount of caffeine.

Historically, the first behavior of caffeine in the
brain to be noticed was the stimulation of the release of
caffeine from intracellular storage sites. (Daly, 1999) In
research done by Garrett and Griffiths (1997) caffeine was
shown to mobilize intracellular calcium by reducing the
calcium uptake and stimulating calcium release. Caffeine
would attach to a calcium channel in this way activating it
and releasing calcium from the "calcium-sensitive"
pool.(Daly, 1999) Due to the importance of calcium
concentrations for the release of neurotransmitters, Garrett
determined, "…mobilization of intracellular calcium has been
proposed as a possible mechanism underlying the behavioral
effects of caffeine" (p.534). However, this determination
was made in vitro and required nearly toxic levels of
caffeine, levels that would rarely be ingested by humans.
(Garrett, 1997; Daly 1999) [See Table 1]

The next effect is the forcing of accumulation of
cyclic adenosine monophospate [cyclic AMP]. This occurs
because caffeine inhibits cyclic nucleotide
phosphodiesterase activity which produces an accumulation of
cyclic AMP. (Garrett, 1997; Myers, 1999) According to the
Pacific Nueropsychiatric Institute "caffeine inhibits
phosphodiesterase breakdown of cyclie 3',-5'-adenosine
monophosphate. (Pharmacology, caffeine, 2) Again, this
occurs only in large quantities that have yet to be
naturally found in vivo. (Myers, 1999) Keep in mind that if
cyclic AMP had a greater than normal concentration in the
synaptic cleft, it would continue to breakdown adenosine
which has a depressant effect on functions in the brain. For
example, adenosine in the central nervous system inhibits
neurotransmitter release and depresses locomotor activity,
however with higher concentrations of cyclic AMP there is
less adenosine so, the effects on the biology of the brain
are an enhanced neurotransmitter release, and stimulated
locomotor activity (Garrett, 1997).

Another way caffeine acts on the brain is indirectly
through the dopamine receptors. As stated by Garrett and
Griffiths (1997), "Although caffeine does not bind directly
to dopamine receptors a number of...

Find Another Essay On Caffeine Effects In The Brain

Caffeine and its effects on the human body

1487 words - 6 pages ," Microsoft® Encarta® Online Encyclopedia 2004] Caffeine, like any other drug, is addictive. The long term effects of caffeine are unhealthy as they change the natural chemistry of the brain, primarily sleep. Adenosine is important to deep sleep because it causes proper reactions in the brain during sleep, yet caffeine interrupts its function. The half-life of caffeine in a human body is about six hours long, meaning that for six

What is the Caffeine Amount in Teas?

2094 words - 9 pages Lemon Zinger contains lemon extracts. Lemon contains citric acid and acid that triggers the brain according to data/ results received from the experiment it is assumed that lemon is stronger than chamomile in fighting stress. This is why Lemon Zinger contained the most caffeine. According to the nutrition fact of Lemon Zinger tea other soothing components such as hibiscus, rosehips, and chicory while the Chamomile tea only contains chamomile. The

The Effect of Caffeine in Daphnia

709 words - 3 pages replacing sleep. A Daphnia is a crustacean commonly found in ponds and lakes. These crustaceans have experimented a change of habitat, which has made their anxiety levels rise up, so many Daphnias' will have a greater heart rate due to anxiety and/or many will die.Structure of CaffeinePredictionMy prediction is that the caffeine will increase the Daphnias' heart rate, as caffeine is a stimulant so the amount of neurotransmitters to be released

The Effects Food has on the Brain

1176 words - 5 pages produced in the brain that have rewarding effects on the body. Opioids control persistent pain and feelings of stress and frustration. This is similar to the effect of drugs, such as morphine and heroin (Kessler, 2009, p.37 ). Stimulating the opioids with food, causes great feelings. This effect drives us to eat more food. “Nucleus accumbens” is the area in the brain that is the center of reward in the body. Opioids that are produced by the

The Effects of Marijuana on the Brain

873 words - 3 pages serious narcotics. Marijuana users experience different sensations, from excessive mellowness, fuzzy memory, to the munchies. Some of the typical effects are impairment of memory, alteration of memory, motor coordination, posture, cognitive ability, and sensory perception. So what is it in marijuana that keeps users wanting more? The active ingredient in marijuana is delta-9-trans-tetrahydrocannabinol, or THC. The structure of THC is very

Effects of drugs on the brain

4271 words - 17 pages in death.Nicotine has direct effects on the brain, which proves that it is an addictive agent. From nicotine the brain develops a certain level at which nicotine is required so that the brain can continue receiving pleasure. This level of satisfaction for the brain becomes larger and more difficult as more nicotine is introduced. Because of this many smokers experience withdrawal symptoms. Nicotine also activates certain neurons in apart of the

The Effects Of Art On The Brain

2926 words - 12 pages are trying to uncover the specific reason of why we enjoy art. One such study even stated that the brain feels “rewarded” when a person is looking at art (Pederson, 1). This study was conducted using four male subjects and four female subjects. The subjects were asked to look at paintings from both famous and non-famous artists. The scientists in charge then used advanced imaging technology to scan the brain while the subjects looked at the

Phantoms in the Brain

1069 words - 4 pages correlate neural anomalies to physiological problems. In his book “Phantoms in the Brain”, V.S. Ramachandran takes aim at a particular section of neural problems – phantom limbs – but explores them through the broader scope of neurobiology. In doing so, he provides a comprehensive assessment of reality – its factors, reasons, and inconsistencies, providing the reader with not only an interesting case study in neurobiology but also an altered perception

Love in the Brain

1418 words - 6 pages Chemistry: New studies analyze love's effects 7) Mating and Temperament 8) What is chemistry and chemicals in love relationships 9) Chemicals 10) Love in the Brain 11) BBC News- Health- How the

effects of marijuana on the brain

1713 words - 7 pages tried marijuana by graduation. Although these individuals may think it is harmless, evidence is stating that the use of cannabis at such a crucial time of development of one’s brain may have long term effects. In this study, Ashtari et al. (2011), examine the effects heavy cannabis usage has on the main brain areas affected by neurogenesis such as the hippocampus and the amygdala, as well as other areas with strong cannabinoid receptors

effects of alcohol on the brain

1880 words - 8 pages see in the news how many accidents are caused by alcohol, yet people still feel the need to drink and drive.Looking back through my research I see that I have a mixture of information. It is hard to say why people drink and drive. Most people know the effects of alcohol on the brain and how it affects their ability to think and make good choices. Yet people still try and drive themselves home. One solution proposed was to lower the acceptable BAC

Similar Essays

The Effects Of Caffeine Essay

1236 words - 5 pages The Effects of Caffeine Works Cited Not Included Caffeine has played a central role in many cultures. Coffee was first discovered over 1000 years ago, and approximately 75% of Americans drink coffee on a regular basis. Despite the thousand years that have passed, there is still controversy surrounding the biological effects of

The Physiological Effects Of Caffeine Essay

2675 words - 11 pages responsible for physiological effects in brain.   In early studies, caffeine was thought to inhibit phosphodiesterase, an enzyme which is responsible for degrading cAMP. This inhibition leads to an increase of cAMP, which is known to have the effects on excitatory neurotransmitters such as norepinephrine and dopamine. Therefore, caffeine would lead to higher activity of the excitatory neurotransmitter causing the stimulatory effects

The Effects On Caffeine During Pregnancy

1286 words - 5 pages ASBTRACT The effects on caffeine during pregnancy were explained and detailed. I explained the causes and effects on caffeine and the major dangers that affect the offspring. Caffeine is the most dangerous cause of danger in pregnancy and their offspring. It can infect the metabolism, the fetal, and can cause miscarriages. The blood flow can easily be decreased by having to much caffeine and can in danger the baby. Why is caffeine dangerous

The Effects Of Caffeine On Salvia Morada

656 words - 3 pages difference in color and shape of the mesophyll, when compared to the controlled sample. I believed this will be due to the dehydrating effects of caffeine, creating a lack of stroma or chlorophyll, thus affecting photosynthesis an in turn, affecting color. I also believe the sample with the energy drink will be healthiest among the exposed sample due to its sugar content.I predicted that the banding results would reveal a difference in banding