The Bubonic plague is caused by a bacterium called Yersinia pestis, this is a gram-negative rod shaped coccobacillus which can infect humans and other animals. This is a very infectious disease, the main form of transmission is fleas being carried by rodents as the fleas allow for the bacteria to cross the skin barrier, and depending on sanitary conditions of the area it can also be transmitted by direct contact and contaminated food. The infection is achievable as the bacteria can suppress or even avoid the normal immune response to foreign bacteria such as phagocytosis and antibody production.
In the late 19th century many manufacturers and builders were using asbestos which has many positive contributes such as fire and chemical resistant, average tensile strength and its affordability. Asbestos is a set of six naturally occurring silicate minerals; it was not known that the prolonged inhalation of these fibres can cause a serious illness called asbestosis which causes the tissue of the lungs to become inflamed when the asbestos fibre penetrates one of the hair sacs in the lung the body tries to destroy the fibre and repair the cells to working condition this process causes the fibre to be covered with a coating that contains iron the tissue in the air sac is replaced with collagen which is stiff and not as flexible and the original lung tissue which leads to shortness of breath, chest pain, dry cough and fatigue. The majority of people developing asbestosis was a person who worked daily with asbestos and is regarded as an occupational lung disease.
Ehlers-Donlos syndrome (EDS) this is an inherited connective tissue disorder. Mutations in the genes affect the structure and production of collagen, collagen is vital as it contributes to the physical strength, joints, muscles, ligaments and blood vessels. This syndrome depends of the severity of the mutation it ranges from mild to life threatening, EDS is caused by a defect in...