This website uses cookies to ensure you have the best experience. Learn more

Current Affairs In Stem Cells Essay

892 words - 4 pages

Publishing Protocol ''Essential technical tips for STAP cell conversion culture from somatic cells'' on 5 March 2014

Despite its seeming simplicity, this procedure requires special care in cell handling and culture conditions, as well as in the choice of the starting cell population. The delivery of the optimal level of sublethal stress to cells is essential to the process of STAP cell induction. From the research team’s experience, STAP conversion was reproducibly seen with culture conditions in which most cells survive for one day after low-pH treatment, and in which up to 80% of the initial cell number subsequently die at around days 2–3. Control of the pH of the solution is not the only ...view middle of the document...

Obokata was accused to plagiarize passages of text and used duplicated images. The first 20 pages of Obokata’s dissertation, completed in 2011 at Waseda University in Tokyo, were found by NatureNews to be taken from US National Institutes of Health webpage on stem cells, and one image in the results section had been reproduced from a commercial website without a citation. However, Vacanti, who was listed on the thesis as a member of the examination committee that approved it, rejected the claim that he had been presented with or asked to read a copy of her dissertation.

One of the research misconducts involved splicing together parts of two photos of electrophoresis gels into figure 1i of the paper and adding The report calls this an "act of research misconduct corresponding to falsification" or in other words, intentionally misleading manipulation. The other problem with the paper was reusing data apparently from Obokata's doctoral thesis, even though the doctoral experiments were significantly different and conducted under different conditions. The reused images appear in figures 2d and 2e of the paper and constituted "an act of research misconduct involving fabrication.

The confusion over the situation worsen when the other research teams such as Prof Lee Ka Ho Kenneth’s team faced failure to reproduce the results. The summary of his research will be explained in following sections.

Another problem with the paper was when part of a description of a method for karyotyping was seen not only copied from a paper published by a separate group, but was also not consistent with the actual procedure that was followed by Obokata’s team. However, the committee...

Find Another Essay On Current Affairs in Stem Cells

Controversy in the Use of Embryonic Stem Cells

1448 words - 6 pages for a long amount of time. If the use of them was not as strictly regulated, the human population could be much more advanced, health wise. A large amount of the embryonic stem cells used for research are left over from in vitro fertilization and donated. If they weren't donated, they would be destroyed, thus losing their incredible potential.
 Embryonic stem cells are classified as pluripotent (“Miracle Cell”). This means they can be grown and

Progress in the Reasearch on Induced Pluripotent Stem Cells

594 words - 3 pages In 2006, Shinya Yamanaka and Kazutoshi Takahashi performed a groundbreaking study in stem cell research. They reprogrammed mouse skin fibroblasts by introduction of four transcription factors, Oct3/4, Sox2, Klf4 and c-Myc and generated cells almost indistinguishable from ES cells. They named these cells induced pluripotent stem cells (iPSCs) (Takahashi K., et al., 2006). An year later, James A. Thomson et al. replaced Oct4 and oncogenic c-Myc

An Essay Analysing The Techniques Used In A Current Affair Program, Referring To Australian Current Affairs Programs

1403 words - 6 pages , barely noticeable techniques that made us believe what they wanted us to believe? How can we notice things as simple as the sex of the presenter, or the choice of words when phrasing something? We think that we are being told the truth. However, this nearly seamless performance is about to be uncovered.The structure in most current affairs shows are similar. It starts off with a presenter giving a rough introduction of the story, then goes to the

Should we use Stem Cells in Order to Cure Other Diseases?

982 words - 4 pages There have been many types of medical advances, but one in particular that has been said that it can help on the treatment of different type of diseases. Stem cells are multicellular organisms that can develop many more of their kind and then give birth to new kind of cells. This types of cells come from the umbilical cord of a new born. This became a huge dilemma where there’s a competing with moral and ethical values. The rumor is a never

In vitro model of human amniotic stem cell differentiation to smooth muscle cells

1971 words - 8 pages Introduction The mechanism of the differentiation of stem cells (SCs) into smooth muscle cells (SMCs) is not yet fully understood, although recent research in this area has made significant strides. In previous studies, human embryonic mesenchymal stem cells (hEMSCs) were shown to differentiate by induction with transforming growth factor beta (TGF-Β) through Smad and serum response factor (SRF), p38 mitogen-activated protein kinase

Ectopic mTERT Expression in Mouse Embryonic Stem Cells Does Not Affect Differentiation but Confers Resistance to Differentiation- and Stress-indu

872 words - 4 pages murine embryonic stem cells was determined because of higher telomerase activity than in humans yielding higher sensitivity. Experiments used overexpression and gene-ablation to study mTERT (murine TERT) where apoptosis resistance/extended cellular lifespan and enhanced sensitivity to cell death/decreased lifespan were observed, respectively. Flow cytometry was coupled with PI exclusion or annexin-5 staining to assess cell death. Conversely

The Heated Debate Concerning Stem Cell Research

3493 words - 14 pages debate, and current policy regarding stem cell research. My personal position will then be juxtaposed alongside supporting and opposing opinions on the matter of Federal funding of embryonic stem cells. Background: What are Stem Cells? Stem cells are a pluripotent cell type, able to differentiate into multiple cell types. There are many kinds of stem cells in the human body, though some are more differentiated to a particular function than

Stem Cell Research Essay

1001 words - 5 pages cells, which can occur as both cell classes, have a limited capacity for self-renewal, but the ability to produce a range of adult cell lines. To date, stem cell therapy (the use of stem cells for medicine) is limited. Re-growth of bone marrow and blood cell production is the height of current technology. Research is currently being undertaken into the abilities of stem cells in healing the body; particularly to regenerate cells and lessen the

All About Stem Cells

1602 words - 7 pages revolution in medicine. Therapeutic stem cell applications have been proposed to address a wide range of health care needs. We are interested in determining the current state of stem cell technology, where stem cells are currently being applied, and evaluating the potential growth for stem-cell-based applications. In particular, we are interested in discerning the current technological state and potential growth of adult stem-cell-based applications as

Stem Cell Research: Should it be Permitted?

1204 words - 5 pages different parts of the body, such as skin, fat, liver, and more, and they’re seeing which are the most easy to manipulate into embryonic stem cells (Ruggles). These are not very well-known, however, so it would take a while for the science to be developed, but the use of these cells is much more humane than that in embryonic stem cells (Stem cell research and therapy: types of stem cells and their current uses). The issue of embryonic stem cell

Stem Cells

1650 words - 7 pages normal tissues have been found in bone marrow. These cells are called haematopoietic stem cells. Haematopoietic stem cells are often referred to as HSCs. HSCs is currently being used to treat blood and immune system diseases, but more current research is being done to test if HSCs can be used to regenerate other types of tissues. There has been some research to support that other tissues have arisen from HSCs (Reya, Morrison, Clarke

Similar Essays

In Support Of Stem Cells Essay

2254 words - 9 pages Though controversial in nature, the extraction, research, and use of human stem cells has been one of the most significant breakthroughs in modern science. The power within these programmable and adaptable cells promises a brighter future for medical advancement such as freedom for those burdened with diseases and disorders. The evidence and factual support for the use of stem cells conveys the gravity of this prospect. Stem cells come from a

Stem Cells In The Brain Essay

1272 words - 5 pages Over the last several years, few areas of medical research have received as much attention as those divisions devoted to stem cell research. Research has uncovered a stockpile of omnipotent cells in many organisms that behave like embryonic cells in that they have the ability to transform into many different cell types. These cells function in injury repair, growth, and regeneration. Stem cell activity has been observed in many areas of the body

Stem Cells In The Treatment Of Diabetes

1601 words - 6 pages Stem Cells in the Treatment of Diabetes Diabetes mellitus affects 18 million people in the U.S. alone (8.7% of the population) and more than 190 million worldwide. The prevalence of diabetes has increased alarmingly in the past three decades and, corresponding to global dietary and lifestyle trends, is projected to nearly double in the next ten years (1). Although diabetes can be treated, serious complications from improperly managed

Stem Cells In The Treatment Of Infertility

2359 words - 9 pages Stem cells in the treatment of infertility Premature ovarian failure (POF) occurs in women under the age of 40 y with primary or secondary hypergonadotropic amenorrhea and accompanied by estrogen deficiency in 75% of cases. None of the women with primary amenorrhea have been reported to ovulate or conceive with their own oocytes, but more than a third of the women were pregnant atleast once before developing hypergonadotropic POF. It is