This website uses cookies to ensure you have the best experience. Learn more

Description Of Duchenne Muscular Dystrophy Essay

1465 words - 6 pages

Description of the Disorder
Duchenne muscular dystrophy is a genetic disorder that is characterized by progressive muscle degeneration and weakness. It is caused by a mutation of the DMD gene that can be inherited through transmission of an X-linked recessive gene. DMD codes for the muscle protein, dystrophin. As a result, people who are affected with this disorder are not able to make this protein in their muscles, causing them to become weak and not function properly (NHGRI, 2014). This disorder moves quickly throughout the body and rapidly gets worse. Of the nine different muscular disorders, Duchenne muscular dystrophy is the most prevalent form found in people today (MDA, 2014).
Epidemiology
Duchenne muscular dystrophy affects approximately 1 in every 3,500 live male births; that is nearly 20,000 new cases annually. This disorder primarily affects young boys because of the disorder’s location on the “X” chromosome. In very rare cases it affects young girls. A majority of the time, it only causes them to become carriers of the disorder and they never show any symptoms. Duchenne muscular dystrophy is not limited to just one race or culture; it affects all races and cultures. Typically, Duchenne muscular dystrophy can be passed down from an affected parent to their child; although, that is not necessarily true in every case. Approximately 35% of children affected with the disorder do not receive it from their parents. This is possible because the disorder can occur in any child when there is mutation on the “X” chromosome where DMD is located. This means that anybody can be affected by this disorder even if it does not run in their family (PPMD, 2014).

Modes of Inheritance
A majority of people diagnosed with Duchenne muscular dystrophy receive the disorder from their mother. If the mother is a carrier of the disorder, her sons will have a 50% chance of having the disease and her daughters would have a 50% chance of being carriers of the disorder. In very rare cases, the daughters may start to show symptoms. If the father had Duchenne muscular dystrophy, he would not be able to pass the disorder on to any of his sons. It is impossible for a son to get the disorder from his father because he receives only the “Y” chromosome from his father which is necessary to make him a male. Duchenne muscular dystrophy is a mutation found on the “X” chromosome so males can only receive the disorder from their mother. Since the father is forced to pass down his “X” chromosome to any females, there is a 100% chance that every daughter will be a carrier of the disorder because the “X” chromosome contains the mutation (MDA,2014).
Duchenne muscular dystrophy is a genetic disorder and is normally passed down from one generation to the next; however, it is still possible for a son to be born with Duchenne muscular dystrophy when there was no family history of the disorder. There are two explanations for why this can occur. First, the mutation that leads to...

Find Another Essay On Description of Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy Essay

817 words - 3 pages I chose this genetic disorder to study because when I read that Duchenne Muscular Dystrophy is diagnosed in young children, my heart went out to those affected by it. This sounded like an interesting subject and this project gave me chance to learn more about the genetic disorder. The scientific name of this genetic disease is Duchenne Muscular Dystrophy, otherwise referred to as Duchenne MD or DMD.DMD is caused by a recessive allele on the X

Duchenne Muscular Dystrophy Essay

763 words - 4 pages Duchenne Muscular Dystrophy is a particularly virulent form of muscular dystrophy that quickly weakens muscles throughout the entire body due to the resulting lack of a functional dystrophin protein that is integral for muscular function. It has a very early onset and spreads quickly, often debilitating the recipients and forcing them to be wheelchair bound well before adulthood. Dystrophin is essential for muscle to maintain its integrity and

Duchenne Muscular Dystrophy

1212 words - 5 pages , DMD is accompanied with occasional use of a wheelchair, and total reliance usually follows by early teens.-----Discovery and Research-----French neurologist, Dr. Guillaume-Benjamin-Amand Duchenne, was not the first to describe this form of muscular dystrophy, but he was the first to study the diseased muscles microscopically.To do this, he invented a tool that removed small portions of tissue located inside the body.-----By developing this tool

Duchenne Muscular Dystrophy - 1139 words

1139 words - 5 pages by early teens.-----Discovery and Research-----French neurologist, Dr. Guillaume-Benjamin-Amand Duchenne, was not the first to describe this form of muscular dystrophy, but he was the first to study the diseased muscles microscopically.To do this, he invented a tool that removed small portions of tissue located inside the body.-----By developing this tool, called Duchenne's trocar, he founded the diagnostic practice of biopsy. After this, he

Genetic Disorders: Duchenne Muscular Dystrophy

1098 words - 4 pages Duchenne Muscular Dystrophy is an inherited genetic disorder that consists of extreme muscle weakness, which rapidly worsens, and over time leads to death. Young newlyweds, Molly and Brent are seeking information on the health of their possible children. Molly’s younger brother, Hunter, has Duchenne Muscular Dystrophy, he suffers and is confined to a wheelchair due to this genetic disorder. Molly and Brent want research done on behalf of their

The Fragile X syndrome and Duchenne muscular dystrophy (DMD) disease comparation

3571 words - 14 pages gene disorder are individual rare and some are named after physicians who described them, for example, Duchenne muscular dystrophy and fragile-X syndrome (Martin-Bell Syndrome) which this paper relates.Fig 1 - DNA showing nucleotides basesFig 2- a) Normal male (46, X Y left) and b) female (46,Xx right) karyotype.·Fragile X SyndromeThe fragile X syndrome is an inhereted disorder, has a incidence of 1 per 4000 males and 1 per 7000 females

Reserch and Treatment of Muscular Dystrophy Disease

653 words - 3 pages Disease Muscular dystrophy is a disease characterized by the weakness and deterioration of skeletal muscles. There are over 30 different forms of muscular dystrophy but the two most common are Duchenne and Becker Muscular Dystrophy (Baroncelli). These two forms of the disease are sex linked, affecting primarily males. A male usually inherits a faulty X chromosome from his mother and receives no other X chromosome to offset the faulty one (males

Muscular Dystrophy

731 words - 3 pages Muscular Dystrophy Scientists have been struggling with the cause, treatment of, and cure for Muscular dystrophy since its discovery in 1886, by Dr. Guillaume Duchenne. Muscular dystrophy is a hereditary disease, affecting thousands of people every year, two-thirds being children between the age of birth through adolescents. Muscular dystrophy can also occur with no family history of the disease. Muscular dystrophy is a degenerating

Muscular Dystrophy (MD)

1240 words - 5 pages Muscular Dystrophy (MD) is a disease that weakens the musculoskeletal system and affects the ability to move. MD also affects groups of muscles. In the 1860’s it was described that boys were progressively growing weaker, losing the ability to move and died at an early age. A decade after the first description a French, neurologist named Guillaume Duchenne gave account for thirteen boys with the most common and severe forms of Muscular

Muscular Dystrophy

1543 words - 6 pages muscles, and eventually they degenerate. Muscular Dystrophy also has several specific types within the disorder, such as: Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and Myotonic Dystrophy. Each one has their own specific characteristics. Muscular Dystrophy is a genetic disorder in which your muscles drastically weaken over time. Muscles are replaced with “connective tissue,” which is more of a fatty tissue than a muscular one. The

This is in indepth look at muscular dystrophy. In this report the causes, the symptoms, and the treatment are discussed pretty throughly

482 words - 2 pages -linked recessive mechanism, virtually all patients are boys. Becker muscular dystrophy is a milder form of Duchenne muscular dystrophy.The facio-scapulo-humeral form of the disease affects both sexes equally and results in weakness and wasting of the shoulder girdle and upper arms. It is usually noted around the onset of puberty. The characteristic weakness of the facial muscles may occasionally be seen during the first years of life. Most patients

Similar Essays

Duchenne Muscular Dystrophy Essay

1388 words - 6 pages Description of the Disorder Duchenne muscular dystrophy is a genetic disorder that is characterized by progressive muscle degeneration and weakness. It is caused by a mutation of the DMD gene that can be inherited in an X-linked recessive fashion. DMD encodes for the muscle protein called dystrophin, and people that are affected with this disorder are not able to make this protein in their muscles (NHGRI, 2014). This disorder moves quickly

Duchenne Muscular Dystrophy Essay 1073 Words

1073 words - 4 pages Duchenne Muscular DystrophyBiology Research PaperMelanie Burns, SCN 3UMs. Hayward28 February 2008Burns - 2Imagine being a parent and discovering that your child won't be able to walk by the age of 12 and won't live past the age of 25. (http://dystrophy.com/muscular-dystrophy/Types+of+Muscular+Dystrophies) This has become a reality for many parents as they find out that their child has a form of muscular dystrophy. This particular type of

Duchenne Muscular Dystrophy Essay 704 Words

704 words - 3 pages Duchenne Muscular DystrophyDuchenne muscular dystrophy is a disorder that involves muscle weakness and loss of muscle tissue that gets progressively worse over time. It starts in childhood and becomes progressively worse over time. Duchenne muscular dystrophy is inherited through a genetic defect on an X chromosome. This disorder is most commonly known to effect males more then females, this is because women have two X chromosomes and the

"Duchenne Muscular Dystrophy" Essay

1124 words - 4 pages you will not live far into your twenties.Pseudohypertrophic Muscular Dystrophy is a dystrophinopathy ("The" 1). The common name for this disease is Duchenne Muscular Dystrophy, or DMD ("What" 1).Duchenne's is the most severe form of dystrophinopathy ("What" 1). This dystrophy is characterized by certain symptoms which are not hard to notice.Some symptoms of Duchenne's are curvature of the spine, abnormal heart function, inability to walk, mental