Isophane (NPH) (Humulin N) (Novolin N) (ReliOn N)
Glargine (Lantus)(Lantus SoloStar)
Regular (Humulin R)(Novolin R)(Regular insulin)(Velosulin)
Glyburide (DiaBeta) (Glynase)
Pioglitazone Hydrochloride (Actos)
Dosing: IV or SC Dose: Available in 100 NPH units/mL SC vials. Also available in combination with regular insulin in 50/50 and 70/30 proportion. ADULTS: TYPE II diabetes: 10 units/day SC at same time each day. Typical insulin dose is .5 -1.0 units/kg/day. Administered SC. PEDS: SC qd/bid. Individualized dose depending on patient. Adolescents may require higher doses. Decrease dose in renal or hepatic impairment. Is a short acting insulin needs to be given 30-60 min before meals or bedtime. Onset 1-2 hrs. peak of 4-14 hours
Dosing: SC or IV. ADULTS: Usual insulin dose .5 – 1.0 units/kg/day PEDS: Usual insulin dose .5 – 1.0 units/kg/day Administered <15 min. before or immediately after meals. SC or via insulin pump. IV in clinical setting only. The dose needs to be adjusted in renal or hepatic impairment. Is a fast acting medication and should be taken within 15 minutes of eating and immediately after mixing. SC onset is <30 minutes, peak 30-90 minutes. Should include longer acting insulin for type I or oral dose for type II
Dosage Form: SC ADULTS: Normal insulin requirement is .5 – 1.0 units/kg/day. PEDS: older than 2 y.o. Need an individualized dose SC. Give this medication <15 minutes before a meal or via SC insulin pump. Dosing may need to be adjusted for renal or hepatic impairment Onset is less than 15 minutes, peak 1-3 hours. If using medication SC, a longer acting insulin for type I or oral for type II. It may me mixed with NPH insulin in syringe
Dosage form: SC: TYPE I ADULTS: use with short –acting or rapid insulin. Start with 0.1-0.2 units/kg SC qpm or with 10 units SC qd-bid for insulin naive patients with Type II diabetes. PEDS: Over 2 years old. Dosing is individualized SC. Typical insulin requirement is 0.5-1 units/kg/day. Dose may need to be decreased in renal or hepatic impairment. Onset is 1 hour, there is no true peak and duration lasts 6-23 hours. Patients with type II may are advised to use this medication with oral or rapid, short-acting insulin. Should not mix Detemir with other insulin in same syringe.
Dosage form: SC ADULT Dose: TYPE I ADULT: individualized dose per patient. Usual insulin dose is .5 – 1.0 units/kg/day. TYPE II ADULT: Begin with 10 units SC qhs, then increase by one unit/day until FPG reached <100 mg/dL. May be used with oral or rapid/short acting insulin PEDS: 6 years and older individualized dose SC Use with rapid or short-acting insulin. Onset one hour, there is no true peak,...