Down syndrome is found in one in every 691 babies in the United States! (Global Down Syndrome Para 12). The abnormality in physical and mental traits of this genetic disease has made it moderately difficult for those who are diagnosed to live. Their lifestyle and their parents are more complicated than a regular human being because of the extra attention towards health and education needed. But with extensive medical care and proper techniques families are able to get through the illness.
Living with Down syndrome can be lethal because of the major medical complications assorted with the disease. Most likely those associated with Down syndrome will suffer from health problems including leukemia, heart defects, hearing loss, Alzheimer's disease and many more. (Learn.Genetics Para 6) These and other difficult issues, risk the chance of a long life expectation. The disease not only affects those who are diagnosed but also those tending to them. They will struggle from the extensive amount of care, costly fundamentals and mental stability brought up from it.
Normal human beings have a total of 46 chromosomes, 23 from each parent. Unlike those with Down syndrome, who have 47 chromosomes, because of a fault during the cell division process. The error is called nondisjunction. Nondisjunction is when chromosomes fail to separate during the metaphase stage. Trisomy 21 is the most common type of Down syndrome named after the 21st chromosome, which is the source of the illness. When the chromosome fails to split in the egg (or sperm) and then join to create an embryo, all the cells in the infant carry 3 copies instead of two, of the 21st chromosome. An extra chromosome can cause a surplus or shortfall of proteins which can harm the body and be lethal for survival.
According to Learn.Genetics “In 90% of Trisomy 21 cases, the additional chromosome comes from the mother's egg” (Learn.Genetics Para 5) Women play a significant position towards the development of getting Down syndrome. Maternal age of a woman majorly reflects the likelihood to have a child with the illness. It is found that women over 35 have a higher risk for their children to have Down syndrome. (A.D.A.M Para 22) Though the genetic disease is mostly initiated by the eggs of females, there is no specific race or gender that the disease is found in.
Down syndrome is the least researched and sponsored genetic disease but is the most common in America. Recent studies have shown they’re able to silence the extra chromosome which halts the extra compounds to be produced. This could majorly affect those with the illness to enable them with less of the disorder and a better health. However, since there are millions of cells in the body with the third copy of the 21st chromosome, it will take years and years to silence all the cells, which could possibly prevent Down syndrome. (Medical News Today)
More medical study would greatly aid scientist, doctors and those with the syndrome to overcome it....