Ebola Virus Infection Treatment & Management

1183 words - 5 pages

“Scientists in Canada announced the successful treatment of Ebola viral infection in monkeys. The encouraging results were published in the journal Science Translational Medicine on June 13.” - www.healthmap.org

Ebola hemorrhagic fever is a viral disease that was first recorded in 1976, when an outbreak occurred in Yambuku, Zaire, a country that was latter renamed the Democratic Republic of Congo (Walsh, Biek & Real, 2005). During the outbreak 318 cases were recorded of which 280 (88%) died. Later the same year, an outbreak occurred in Sudan where 284 cases were recorded with fatality rate of 53%. The disease and the virus that cause it are named after River Ebola that passes though Yambuku. In the USA, Ebola killed several monkeys in Reston, Virginia in 1989 (Barton, 2006; CDC, 2000). Despite several other outbreaks, the disease has neither medically approved pre-exposure nor post-exposure interventions. However, ongoing research shows optimistic signs.

The early symptoms of Ebola hemorrhagic fever are characterized by high fever, chills, malaise and myalgia. The next phase of the disease is characterizes by hematemesis, (the vomiting of blood), diarrhea with blood, abdominal pain, and drained of physical strength, sore throat, edema, confusion, and uncontrolled bleeding at venipuncture sites (Bardi, 2002; Hensley, Jones, Feldmann, Jahrling, & Geisbert, 2005).

The virus has direct impact on the immune system, and it is known to infect macrophages. It has been hypothesized that infection of macrophages is one of the causes for development of hemorrhage. The virus also causes high production of cytokines. Due to infection, lymphocytes die in large numbers, causing reduction of T-cells and natural Killers (Hensley, Jones, Feldmann, Jahrling, & Geisbert, 2005).
The virus also infects endothelial cells, where most replication occurs. Infection endothelial cell may be the main cause of hemorrhage and vascular damage. When tested for Ebola viral antigens, some endothelial cells of tissues used for autopsy have shown positive results (Hensley, Jones, Feldmann, Jahrling, & Geisbert, 2005).

Apart from human, Ebola also infect other primates including gorillas and chimpanzees (Walsh, Biek & Real, 2005). The virus has also been found in the fruit bat. In a research conducted by Leroy and colleagues IgG antibody to Ebola was recorded in 8.3% of the fruit bats under study. This study hypothesized that fruit bats are the natural reservoir for Ebola virus. According to results of laboratory studies, fruit bats have been able to support replication of Ebola Virus without showing any symptoms of Ebola hemorrhagic fever (Leroy, Kumulungui, Pourrut et al. 2006).

Because the most common form of infection remains direct contact with bodily fluids (Bardi, 2002), it has been suggested Ebola infected human when hunters came in to contact with infected primate carcasses. During the first outbreak, with little knowledge of the mode of infection,...

Find Another Essay On Ebola Virus Infection Treatment & Management

The Ebola Virus Essay

624 words - 2 pages blood vessels. Certain levels of this protein could determine the chances of survival of an infected person. Scientists are also trying to develop a cure by utilizing the benefits of this protein. Currently, there are 2 possible vaccines that are being tested to see if they will prevent the virus. Since there is no  preventative treatment for the Ebola virus currently and treatment is only experimental, we have to take careful measures in order

Ebola, its transimission, symptoms, signs, treatment, history, research, etc

1319 words - 5 pages treatment that can be given to Ebola victims is support. They are usually very dehydrated and need management of fluid and electrolyte balance. Victims may sometimes require IV feeds to replace liquids. Before shock occurs it may be helpful to replace plasma albumin. There is currently no cure or vaccine for the Ebola virus., although it is recorded that someone in the United Kingdom was infected with Ebola Zaire and was injected with the plasma of

Public Health Problems: Ebola Virus

1742 words - 7 pages immunity, which can in turn prevent people from getting the Ebola virus. The six ways that we can improve our health and prevent getting Ebola virus, are by avoiding traveling to areas of known outbreaks, washing of the hands frequently, by avoiding consumption of bush meat, by avoiding close contact with infected people, by following infection-control procedures, and by not handling remains. The first way is to avoid traveling to areas of known

Treatment for Ebola

958 words - 4 pages and are tested for specific antigens, antibodies or the virus’s genetic material itself. Recently, a skin test has been developed which can detect infections much faster. A skin biopsy specimen is fixed in a chemical called Formaline, which kills the virus, and is then safely transported to a lab. It is processed with chemicals and if the dead Ebola virus is present, the specimen will turn bright red. There is no specific treatment against the

ebola

1230 words - 5 pages transcribed, producing mRNA which is used to produce the virus' proteins. The RNA is replicated in the cytoplasm and is mediated by the synthesis of an antisense positive RNA strand which serves as a template for producing additional Ebola genomes. As the infection progresses, the cytoplasm develop "prominent inclusion bodies" which means that it will contain the viral nucleocapsid that will become highly ordered. The virus then assembles and buds off

The Ebola virus

1687 words - 7 pages unknown. Once the virus is inside a cell, the RNA is transcribed and replicated. The RNA is transcribed, producing mRNA which are used to produce the virus' proteins. The RNA is replicated in the cytoplasm and is mediated by the synthesis of an antisense positive RNA strand which serves as a template for producing additional Ebola genomes. As the infection progresses, the cytoplasm develops 'prominent inclusion bodies' which means that it will

Ebola hemorrhagic fever (Ebola HF)

1151 words - 5 pages infection with the Ebola virus, are suspected. Researchers don't understand why some people are able to recover from the virus and others are not. It is known that the patients who die usually have not developed a significant immune response to it at the time of death. The virus can easily spread through several ways. People can be exposed to it from direct contact with infected blood or secretions. So the virus is often spread through family

The Ebola Virus

1152 words - 5 pages make it to this stage of development (Martin, J.E., Sullivan, N.J., Enama, M.E., Gordon, I.J., et al. 2006).  Viruses cause many deadly diseases in humans, one of the deadliest being hemorrhagic fever. Its rapid onset of symptoms and chronic infection of vital organs has made treatment extremely difficult. Ebolavirus, a virus known to cause this disease and produce high rates of fatality within populations, has been prominent in countries of

The Ebola Virus

1102 words - 4 pages , and virus isolation are a couple of examples of the types of laboratory testing that can be done to diagnose and Ebola patient. Because of how easily it can be transmitted, it is extremely difficult to treat and there is no approved, official treatment. As of now, there is not standard treatment but usually the patients are given fluids and oxygen, have their blood pressure monitored and other necessary treatment. To prevent transmission and

Ebola One of the Most Deadly Diseases of the New Age

1463 words - 6 pages One of the most deadly diseases of the new age, basically has the same properties of a microwave and is able to liquefy the human body from the inside out. This disease is known as the Ebola hemorrhagic fever, also known as (EHF). EHF first was recorded in Sudan and Zaire in Africa. The initial recording of the virus infected 284 with a high mortality rate of 53%. The initial reservoir or transportation of the virus was not identified as the

Ebola Virus - information on the virus **School Essay**

526 words - 2 pages The Ebola virus is a deadly virus in the filovirus family. The filovirus family consists of Ebola Zaire, the most virulent of the Ebola viruses, Ebola Sudan, Ebola Reston, and Marburg. The Ebola Zaire virus has a 90% kill rate but has not been proved to be airborne. Ebola Zaire brokeout in 1976 and killed around 500 people according to most sources. Ebola Sudan is less virulent but still kills almost 70% of all it's victims over 50%more then

Similar Essays

The Ebola Virus. In Depth Research Paper About The Ebola Virus. Disscusses Infection, Spread, Mortality Rates, Different Strains And Outbreaks

1337 words - 5 pages The ebola virus is a very complex level four virus. Level four viruses are extremely lethal, and there is no cure for them yet, not does there seem to be a cure for them or ebola in the near future. To give you an example of just how lethal level four viruses like ebola are, AIDS is only a level three virus, and requires minimal protection when working with it. The protection required for working with the ebola virus consists of wearing three

Management Of Chronic Hepatitis B Virus Infection

933 words - 4 pages guidelines: Management of chronic hepatitis B virus infection’’[J Hepatol 2012; 57: 167--185]. Journal of Hepatology. 2013;58:201. 3. Scaglione S, Lok A. Effectiveness of hepatitis B treatment in clinical practice. Gastroenterology. 2012;142(6):1360--1368.

The Ebola Virus Essay 1194 Words

1194 words - 5 pages ). The Ebola virus has severe and disgusting symptoms. After the time it takes to take effect the Ebola virus starts out by showing symptoms like the flu. You develop a sore throat, fever, weakness, muscle pain, and headaches. As the virus progresses vomiting, diarrhea, rash, and limited kidney and liver function. After about 14 days of infection, bleeding becomes uncontrollable. Blood passes through eyes, lips, nose, ears, and skin. You also

Ebola Hemorrhagic Fever Essay

1525 words - 6 pages Ebola Hemorrhagic Fever Ebola hemorrhagic fever (Ebola HF) is a severe, often-fatal disease in humans and nonhuman primates (monkeys and chimpanzees) that has appeared sporadically since its initial recognition in 1976. The disease is caused by infection with Ebola virus, named after a river in the Democratic Republic of the Congo (formerly Zaire) in Africa, where it was first recognized. The virus is one of two members of a