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Excess Dietary Protein And Hypercalcuria. Calcium.

2306 words - 9 pages

INTRODUCTION:Osteoporosis is the major public health problem in the United States because the disease costs million lives and dollars. Osteoporosis, which means "porous bones," is a condition of excessive skeletal fragility resulting in bones that break easily. A combination of genetic, dietary, hormonal, age-related, and lifestyle factors all contribute to this condition. Osteoporosis leads to 1.5 million fractures, or breaks, per year, mostly in the hip, spine and wrist, with the cost of treatment estimated at $10 billion to $15 billion a year, according to the National Institutes of Health. It threatens 25 million Americans, mostly older women and men. One in three women past 50 will suffer a vertebral fracture, according to the foundation (Munger 147). These numbers are predicted to rise as the population ages. Most causes of osteoporosis are uncontrollable, such as genetics and ages. However, there are also dietary factors and living lifestyles that contribute greatly to the disease. For more than half a century there were studies and research, which showed that that diets high in protein increase calcium resorption from bone and urinary calcium excretion, thus, increasing the risks for osteoporosis and other diseases (Munger 149-52). First, this paper will give evidences about how diets that are high in protein contents can cause hypercalciuria. Second, it will give the mechanism of how hypercalciuria is caused. Lastly, it will present what types of people are affected by this disease, and how diets high in fruit and vegetables can reverse the process.THE EVIDENCES:There were many researches and studies, which proved that high consumption of dietary protein could lead t urinary calcium excretion, and eventually caused hypercalciuria. One of those evidences was a study conducted by Dr. Jane Kerstetter at the School of Allied Health. His study concluded that high levels of dietary protein increased urinary calcium excretion and induced negative calcium balance. The experiment had sixteen healthy women (aged 20-40 yr) as participants. The control was a two-week diet containing moderate amounts of calcium, sodium, and protein. Followed the control was the experimental diet, which was four days long and consisted of one of three levels of protein (low, moderate, or high). On day four, serum and urinary calcium, serum PTH, 1,25-dihydroxyvitamin D, serum osteocalcin, bone-specific alkaline phosphatase, and urinary N-telopeptide excretion were measured (Kerstetter 1053-4). The cycle of a 2-week adjustment period and a 4-day experimental period was repeated two more times until all subjects received each of the three levels of dietary protein in random order. The study was approved by human investigation committees at both Yale University and the University of Connecticut. After the experiment has been completed, the results showed significant high levels of urinary calcium and N-telopeptide excretion on the high protein diet. The study concluded...

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