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Genetics, Genetic Research And Cloning The Human Genome Project

1996 words - 8 pages

Eight page paper outlining the Human Genome Project, a research study and project involving cloning of DNA for medical and research use. Written as an ethical issues paper from a nurse's standpoint. It includes the history of the project and uses today and in the future. Also includes potential ethical issues regarding cloning. Complete with references in APA format.Running head: GENETICS, GENETIC RESEARCH AND CLONINGGenetics, Genetic Research and CloningThe Human Genome ProjectMelissa A. BuzbeeUniversity of WyomingWhen James Watson won the Nobel Prize in Medicine in 1962 for discovering the structure of DNA, he opened up a whole new area of science and research that has led to great strides in medicine, as well as great controversy.Beginning in the 1960's and 1970's, nearly all avenues of biomedical research have led to the gene, for genes containing the basic information about how a human body carries out its duties from conception until death (Collins, 1999). As new technologies and advancements in understanding DNA were developed in the 1980's, it became clear that mapping DNA's sequences and the entire human genome was essential. With this realization a project entitled the Human Genome Project (HGP) was born.The Human Genome Project officially began in 1990 under the leadership of the National Institute of Health (NIH) and the National Human Genome Research Institute (NHGRI). The goal of the HGP was to determine the location of all human genes and to read the entire set of genetic instructions encoded in human DNA (NHGRI, 2003). During the first half of the decade, the HGP primarily dedicated itself to developing genetic and physical maps pointing out precise locations of individuals' genes. By 1997, these studies had successfully sequenced approximately 2% of human DNA. This information was made readily available to the public in open databases so that anyone interested in the sequencing of DNA had immediate access to the most current information. The world wide sharing of research findings enabled scientists to progress more rapidly and by June 2000, the International Human Genome Sequencing Consortium announced a "working draft" sequence of the human genome, nearly 90% complete, had been produced (NHGRI, 2003). In April 2003, the Human Genome Project officially met itsgoal, two years ahead of time and under budget, by producing a finished sequence completely mapping all human DNA.Genetic research has been utilized in all areas of therapeutic and preventive health care as well as pharmacogenomics, forensics, microbiology and agricultural research. By far, the most proliferant area benefitted by genome identification is medicine. By improving our insight on how human genes work, scientists are better able to discover new and more effective treatments for diseases. Recent successes by NHGRI's intramural researchers include discovery of genes for prostate cancer, breast cancer, holoproscencenphaly, progeria and Alzheimer's disease. Once...

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