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Hepatitis E Essay

1337 words - 5 pages


Disease!!!!! Disease!!!! Disease!!!! Living on this earth we are exposed to a lot of different infectious Disease. Hepatitis E is a very serious liver disease caused by the Hepatitis E virus (HEV) that usually results in an acute infection.( It’s safe to safe to say that Hepatitis E does not lead to a chronic infection according to CDC. In this research paper I will identify the causative agent, geographical distribution, transmission, clinical features, diagnosis, treatment, and the control measures of this serious liver disease. Key facts about Hepatitis E may include:
• Every year there are 20 million hepatitis E infections, over 3 million acute cases of Hepatitis E, and 57,000 hepatitis E related deaths.
• Hepatitis E is found worldwide, but the prevalence in highest in East and South Asia
• Hepatitis E is usually self limiting but may develop into fulminant hepatitis and is transmitted via faecal-oral route, principally via contaminated water.
• China has produced and licensed the first vaccine to prevent hepatitis E virus infection, although it is not yet available globally.

The Causative Agent

The causative agent for hepatitis E is the Hepatitis E virus (HEV). According to my research the virus originated from the stool of a volunteer orally infected with faces from suspect cases of non-A and non-B hepatitis (Balayan et al. 1983) hepatitis E virus is a non-eveloped, positive-sense, single-stranded ribonucleic acid (RNA) virus is approximately 27 to 30 nm in size (veterinami medicina 52, 2007) (HEV) infections are spreads by the faecal – oral route and causes acute sporadic and epidemic viral hepatitis worldwide, usually through contaminated water supply. (Vasickova et al, 2005) However, the actual mechanism allowing the virus to reach the site of primary multiplication has not been fully identified and clarified. (Veterinarni] medicina, 52, 2007). There is also a possibility of zoonotic transmission of the virus. (HEV) has 4 genotypes; of the 4, land 2 is known to infect only humans, whereas genotypes 3 and 4 primarily infect other mammals. Seroepidemiological studies redealed that anti HEV antibodies are presents in numerous animals species including pigs, shellfish, rodents, chickens, dogs, cows, sheep and goats from developing and industrialized countries (Tien et al. 1997, favorov et al., 1998, Aran Kalle et al., 2001). HEV is the only member of the hepevirus genus. Hepaviridae family. (Emerson et al. 2004).


The incubation period following exposure to the Hepatitis E virus ranges from three to eight weeks, with a mean of 40 days. The period of communicability is unknown. According to my research the hepatitis E virus cause what we call an acute sporadic and a epidemic viral hepatitis. Symptomatic infection is most common in among adults aged from 15 to 40 years old. Also although infection is frequent in children, the disease is mostly asymptomatic or causes a very mild...

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