Huntington's Chorea Essay

1352 words - 5 pages

Huntington's chorea, or Huntington's disease, named after Ohio physician George Huntington in 1872, is an inherited disorder characterized by abnormal body movements called chorea, and loss of memory. Chorea is an abnormal voluntary movement disorder, one of a group of neurological disorders called dyskinesias, which are caused by overactivity of the neurotransmitter dopamine in the areas of the brain that control movement. Chorea is characterized by brief, irregular contractions that are not repetitive or rhythmic, but appear to flow from one muscle to the next. The incidence is 5 to 8 per 100,000. Understanding and treating Huntington's chorea can help save countless lives and individuals.A genetic disorder, or genetic disease, is a disease caused by abnormal expression of one or more genes in a person causing a distinct phenotype. There are a number of possible causes for genetic defects. They may be caused by a mutation in a gene, affecting its function. There are genetic disorders caused by the abnormal chromosome number, Down syndrome and Klinefelter's syndrome. Defective genes are often inherited from the parents. In this case, the genetic disorder is known as a hereditary disease. This can often happen unexpectedly when two healthy carriers of a defective recessive gene reproduce, but can also happen when the defective gene is dominant. A number of genetic disorders are due to the change of a single gene, resulting in an enzyme or other protein not being produced or having altered functionality, called monogenic disorders. The change can be trivial and relatively harmless in its effects, such as color blindness, or lethal such as Tay-Sachs. Other disorders, though harmful to those afflicted with them, appear to offer some advantage to carriers. For example, carriers of sickle cell anemia appear to have enhanced resistance to malaria. Several hereditary diseases are sex-linked, meaning that they afflict one sex much more common than the other because the mutation is located on the X or the Y, although rarely, chromosome (Jackson 37).Genetic disorders may also be complex, multifactorial or polygenic, this means that they are likely associated with the effects of multiple genes in combination with lifestyle and environmental factors. Multifactoral disorders include heart disease and diabetes. Although complex disorders often cluster in families, they do not have a clear-cut pattern of inheritance. This makes it difficult to determine a person's risk of inheriting or passing on these disorders. Complex disorders are also difficult to study and treat because the specific factors that cause most of these disorders have not yet been identified. One common example of a polygenic disorder is autism (Harris L. 13).Genetic disorders can be inherited in six ways: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y-linked, and mitochondrial. Autosomal dominant requires only one affected parent for the children to have it....

Find Another Essay On Huntington's Chorea

Detection of Huntingtons' Chorea Essay

871 words - 3 pages For the average person the idea of a health issue is the occasional upset stomach or catching the flu. Imagine living each gradual day losing a little more control over the use of muscles and nerves. Huntington’s Chorea is a neurodegenerative genetic disease that proves to have a devastating effect and has many varied methods of testing. Huntington’s Chorea, also known as Huntington’s Disease or HD, is a incurable genetic disorder that causes

Huntington’s Chorea Essay

1479 words - 6 pages , Huntington’s Chorea is an autosomal dominant trait. This means that the trait is not sex- linked, but gets passed on normally. If one parent has Huntington’s Disease, then there is a fifty percent chance of the child getting Huntington's. If both parents have homozygous dominant for Huntington’s, then there is a seventy- five percent chance of the child getting Huntington’s. If a generation of a family have Huntington’s, the number of CAG repeats

Huntington's Disease

3443 words - 14 pages Huntington's Disease. There is currently no cure, so to those who develop the disease, it is lethal. The most characteristic feature, and the symptom which is used to first diagnosis Huntington's, is chorea. Chorea can be characterized by a series of tics affecting the face and limbs. In more advanced Huntington's the chorea turns into athetosis or dystonia in which the affected person experiences a "writhing quality" (Furtado 7). There are

The Divastatin Hereditary Huntington's Disease

1625 words - 7 pages Huntington's Disease is “a devastating, hereditary, degenerative brain disorder for which there is, at present, no cure... HD slowly diminishes the affected individual's ability to walk, talk and reason. Eventually, the person with HD becomes totally dependent upon others for his or her care” (What is Huntington’s Disease). The “penetrance of the gene [is] close to 100% by old age but is low during the years of reproductive life” (Prediction and

Huntingsons diease

1101 words - 4 pages Huntington's Background Huntington's disease is inherited as an autosomal dominant disease that gives rise to progressive, elective (localized) neural cell death associated with choleric movements (uncontrollable movements of the arms, legs, and face) and dementia. It is one of the more common inherited brain disorders. About 25,000 Americans have it and another 60,000 or so will carry the defective gene and will develop the disorder as they age

Taking a Closer Look at Huntington's Disease

1219 words - 5 pages “Huntington's disease (HD) is the result of a genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain” (NINDS). The condition has been named after George Huntington, the finding physician who first discovered ands defined it in the late 1800s.The flawed gene code shows a blueprint for a protein called huntingtin (Huntington's Disease). This protein’s role is not yet known, but it's called "huntingtin" do

Hunting Down Bad Genes

2048 words - 8 pages Disease." USA Today (Farmingdale). Sept. 2001: 34-35. SIRS Issues Researcher. Web. 20 Mar. 2014. Gorner, Peter. "2 Americans Share Nobel Prize for Medicine." Chicago Tribune (Chicago, IL). Oct. 2 2006: n.p. SIRS Issues Researcher. Web. 18 Mar. 2014. "Huntington's chorea/disease." World of Health. Gale, 2007. Science in Context. Web. 21 Mar. 2014. Hayden, Thomas. "DNA Meets Its Match." U.S. News & World Report. Feb. 24 2003: n.p. SIRS Issues

Huntington's Disease - An Overview

1187 words - 5 pages degrees, and often occupying years in its development until the hapless sufferer is but a quivering wreck of his former self". The three most profound behavioral problems in Huntington 's disease come from the uncontrollable movements called "chorea," dementia, and the altered perception of the world. The course of Huntington's Disease can last anywhere from ten to 30 years from onset to death. The symptoms of HD usually develop when th e person

Huntington's disease

1011 words - 4 pages Huntington's BackgroundHuntington's disease is inherited as an autosomal dominant disease that gives rise toprogressive, elective (localized) neural cell death associated with choreic movements(uncontrollable movements of the arms, legs, and face) and dementia. It is one of themore common inherited brain disorders. About 25,000 Americans have it and another60,000 or so will carry the defective gene and will develop the disorder as they

Your birth Biography: Genome, the Autobiography of a Species in 23 Chapters

1065 words - 5 pages , but once that is decided, there is either a 100% chance you will get the disease or 0% chance. If you are tested for Huntington's chorea the result of positive or negative is absolute and guaranteed. In addition, the approximate age at which you will get the disease is almost just as certain, it is relative to the number of extra CAD repeats you have. But going back to the point at the beginning of this paragraph, Ridley used a very touching

Disorders of the Nervous System: Huntington’s disease

1022 words - 5 pages Disorders of the Nervous System: Huntington’s disease Huntington’s disease destroys the organs that carry the functions of the central nervous system. Kalat (2013) states, “Huntington disease (also known as Huntington disease or Huntington’s Chorea) is a severe neurological disorder that strikes about 1 person in 10,000 in the United States” (A.B. Young, 1995, p. 258).Individual’s develop the symptoms in their middle age, but even if it is a

Similar Essays

Huntingtons Disease Essay

994 words - 4 pages Huntington's Disease Huntington's disease, also known as Huntington's chorea is a genetic disorder that usually shows up in someone in their thirties and forties, destroys the mind and body and leads to insanity and death within ten to twenty years. The disease works by degenerating the ganglia (a pair of nerve clusters deep in the brain that controls movement, thought, perception, and memory) and cortex by using energy incorrectly. The brain

Huntington's Disease Essay

1003 words - 4 pages Old essay, lots o' content, just needs a good proofread -HUNTINGTON'S DISEASEHuntington's disease, also known as Huntington's chorea is a geneticdisorder that usually shows up in someone in their thirties and forties,destroys the mind and body and leads to insanity and death within ten totwenty years. The disease works by degenerating the ganglia (a pair of nerveclusters deep in the brain that controls movement, thought, perception, andmemory

Huntington's Disease Essay

690 words - 3 pages Huntington's DiseaseHuntington's disease, or Huntngton's chorea, is a genetic disease that causes selective neural cell death, which results in chorea, or irregular, jerking movements of the limbs caused by involuntary muscle contractions, and dementia. It can cause a lack of concentration and depression. It also may cause atrophy of the caudate nucleus, a part of the brain. However, symptoms vary between individuals, with some sufferers showing

Huntingtons Isease Essay

675 words - 3 pages ! Huntington disease is a progressive brain disorder that causes uncontrollable movements, emotional problems, and loss of thinking(What is huntington's Disease 1). You also might know Huntingtons disease as Chorea, huntington chronic progressive, or heready chorea. Huntingtons affects every 3-7 per 100,000 person. It does not matter what gender you are it affect both male and female the same. HD (Huntingtons disease) is most commonly found in