This website uses cookies to ensure you have the best experience. Learn more

Huntington's Disease Essay

1551 words - 6 pages

Huntington’s Disease is a brain disorder affecting movement, cognition, and emotions (Schoenstadt). It is a genetic disorder generally affecting people in their middle 30s and 40s (Sheth). Worldwide, Huntington’s disease (affects between 3-7 per 100,000 people of European ancestry (Schoenstadt). In the United States alone, 1 in every 30,000 people has Huntington’s disease (Genetic Learning Center). Huntington’s Disease is a multi-faceted disease, with a complex inheritance pattern and a wide range of symptoms. There is also much research being done in the field of Huntington’s disease, because as of 2012, this disease is untreatable. THESIS.
George Huntington first described Huntington’s disease in 1872, but it was only mentioned to the world in 1913, when “Huntington’s chorea,” the disease’s original name, appeared on the agenda of a Washington medical convention (Bakalar). In 1936, Huntington’s disease was mentioned twice, in two different letters about eugenics, “improving the species by regulating human reproduction,” (Bakalar). It appeared as one of five diseases that should be considered for voluntary sterilization (Bakalar). The first description appeared in an article titled, “Report on a Hereditary Illness,” that described the study of Huntington’s that had been published in a British medical journal (Bakalar). The study, which found the illness to be more widespread than thought, mentioned George Huntington and his original work and included a description of the disease’s symptoms and prevalence (Bakalar). On October 4, 1967, Huntington’s disease made an appearance in the obituary of well-known folk singer and composer Woody Guthrie, who suffered from the disease for thirteen years.
In normal circumstances, every child receives genetic information (chromosomes) from both parents, 23 from the mother and 23 from the father (Appai-Kubi). Every cell within the body contains this entire set of chromosomes, which have bases arranged to form a code (Appai-Kubi). The four bases, cytosine, adenine, guanine, and thymine, interact to form the fundamental structure of DNA (Appai-Kubi). Huntington’s Disease is found on the fourth chromosome, with a sequence known as the “CAG repeat,” (Appai-Kubi). In someone who is not afflicted, the number of CAG repeats ranges from 10 to 28 (Sheth). Typically, more than 35 repetitions of CAG is associated with Huntington’s Disease, however, there are cases with people having up to 39 repeats not having the disease (Appai-Kubi). As the gene is passed on through families, the number of repeats generally increases, and with an increased number of CAG repeats, the earlier the symptoms develop (Sheth). This characteristic of the disease allows it to be tested for, by testing the frequency of CAG on chromosome 4 (Appai-Kubi.) During pregnancy, a woman can test for Huntington’s Disease in two ways; either amniocentesis, taking fluid from around the fetus, or by CVS, taking a sample of fetal cells from the placenta...

Find Another Essay On Huntington's Disease

Huntington's Disease Essay

3443 words - 14 pages Huntington's Disease A shadow of love doesn't have arms to embrace you, to make you feel wanted and secure. It only blocks out the warmth of what could be. -Jean Miller, a woman whose daughter Kelly died of Huntington's Disease A woman stares pensively out her bedroom window. Today is her twenty-seventh birthday. Most people have the whole rest of their lives to look forward to when staring out the window at this age, but not

Huntington's disease Essay

1011 words - 4 pages Huntington's BackgroundHuntington's disease is inherited as an autosomal dominant disease that gives rise toprogressive, elective (localized) neural cell death associated with choreic movements(uncontrollable movements of the arms, legs, and face) and dementia. It is one of themore common inherited brain disorders. About 25,000 Americans have it and another60,000 or so will carry the defective gene and will develop the disorder as they

Huntington's Disease

1708 words - 7 pages and Mason Academy of Medicine at Middleport, Ohio, in 1872,” (Folstein). Shortly after 1900, papers on Huntington’s disease gradually began appearing in case reports and psychiatric literature (Folstein). In 1936, Huntington’s disease appeared twice in two different letters to an editor about eugenics, which is defined as “improving the species by regulating human reproduction,” (Bakalar). These letters named Huntington's disease as one of five

Huntington's Disease

1325 words - 6 pages Huntington's Disease In 1872, George Huntington, American physician, researched and published a report on a disease that affected several generations of a family in East Hampton on Long Island. The clinical manifestations reflected Huntington’s disease (HD) with chorea, psychiatric and cognitive impairment and slow progression of deterioration leading to death. Huntington’s disease is an autosomal- dominant neurodegenerative disorder that is

Huntington's Disease - An Overview

1187 words - 5 pages Huntington's Disease - An Overview Huntington's Disease is a devastating and progressive neurological disorder that resu lts primarily from degeneration of nerve cells deep in the center of the brain. The condition was first described by George Huntington, a physician in New York, in 1872. Even then, the physician recognized the all-encompassing factors of the disorder when describing it as, "coming on gradually but surely, increasing by

Summary of Huntington's Disease

1296 words - 6 pages would enhance this study because females certainly differ biologically from males and may therefore experience different effects of Huntington’s. The knowledge gained as a result of these differences may be beneficial in treating Huntington’s in male and female patients. Works Cited Wider, C., & Lüthi-Carter, R. (2006). Huntington's disease: Clinical and aetiologic aspects. Schweizer Archiv Für Neurologie Und Psychiatrie, 157(8), 378-383

The Divastatin Hereditary Huntington's Disease

1625 words - 7 pages Huntington's Disease is “a devastating, hereditary, degenerative brain disorder for which there is, at present, no cure... HD slowly diminishes the affected individual's ability to walk, talk and reason. Eventually, the person with HD becomes totally dependent upon others for his or her care” (What is Huntington’s Disease). The “penetrance of the gene [is] close to 100% by old age but is low during the years of reproductive life” (Prediction and

Huntington's Disease and Its Ethics

1008 words - 4 pages Huntington's Disease and Its Ethics In “Genetics and Reproductive Risk: Can having children be immoral,” L.M Purdy discusses the notion that the recent advances in reproductive technology impose a moral obligation on individuals to prevent the birth of “affected” babies that will not have a “minimally satisfying life.” There are, however, several assumptions that the author makes in reaching the conclusion that

Taking a Closer Look at Huntington's Disease

1219 words - 5 pages “Huntington's disease (HD) is the result of a genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain” (NINDS). The condition has been named after George Huntington, the finding physician who first discovered ands defined it in the late 1800s.The flawed gene code shows a blueprint for a protein called huntingtin (Huntington's Disease). This protein’s role is not yet known, but it's called "huntingtin" do

Huntington's Disease

1022 words - 5 pages Huntington’s disease (HD) is rare genetic neurodegenerative disease. The neurons in the brain progressively during a person’s lifetime degenerate to a point where the brain’s motor, cognitive, and psychiatric functions are affected. The symptoms from these disturbances can include, unintended weight loss, sleep and circadian rhythm disturbances and autonomic nervous system dysfunction. The average age of the symptoms onset is generally between

Analysis of Huntington's Disease

2348 words - 10 pages Huntington’s Disease (HD) is a genetically transferred, progressive neurodegenerative disease that is caused by a defect on chromosome 4. The chromosomal defect is inherited through an autosomal dominant gene and causes a cytosine-adenenine-guanine (CAG) repeat to occur more often than expected., which codes for an abnormality in the protein called huntingtin. When the huntingtin protein has mutated, cells are not able to carry out their

Similar Essays

Huntington's Disease Essay

1003 words - 4 pages Old essay, lots o' content, just needs a good proofread -HUNTINGTON'S DISEASEHuntington's disease, also known as Huntington's chorea is a geneticdisorder that usually shows up in someone in their thirties and forties,destroys the mind and body and leads to insanity and death within ten totwenty years. The disease works by degenerating the ganglia (a pair of nerveclusters deep in the brain that controls movement, thought, perception, andmemory

Huntington's Disease Essay

690 words - 3 pages Huntington's DiseaseHuntington's disease, or Huntngton's chorea, is a genetic disease that causes selective neural cell death, which results in chorea, or irregular, jerking movements of the limbs caused by involuntary muscle contractions, and dementia. It can cause a lack of concentration and depression. It also may cause atrophy of the caudate nucleus, a part of the brain. However, symptoms vary between individuals, with some sufferers showing

Huntington's Disease Essay 543 Words

543 words - 2 pages Huntington's DiseaseHuntington's Disease (HD) is an inherited conditions characterized by abnormal body movements, dementia, and psychiatric problems. Huntington's Disease is a progressive disorder involving degeneration of nerve cells in the brain. It is one of the more common inherited brain disorders. About 25,000 Americans have it and another 60,000 or so will carry the defective gene and that binds itself to the Huntington molecule only in

Huntington's Disease Essay 1274 Words

1274 words - 5 pages Huntington's Disease Huntington's Disease is a genetic autosomal disorder which effects the brain. It affects about 1 in 20,000 individuals. The symptoms of the disease do not start to occur until after or around 40 years of age. With the onset of the disease the patient starts to gradually deteriorate intellectually, this deterioration also causes involuntary movements. Scientists have only recently found the section of the gene which