Infertility, Insulin Resistance, Polycystic Ovary Syndrome And Myo Inositol

2344 words - 10 pages

Polycystic ovary syndrome is an endocrine disorder that affects at least 10% of women living in the United States. Insulin Resistance plays a large part in fertility for women who have polycystic ovary syndrome. Myo-Inositol improves fertility, and alleviates many of the symptoms associated with polycystic ovary syndrome and insulin resistance.
Polycystic ovary syndrome is a condition that affects many different parts of the body, not just the ovaries. The list of ailments associated with polycystic ovary syndrome is long, ranging from skin tags, dark skin patches, and hirsutism (male patterned hair growth) to liver disease, obesity, and insulin resistance. The symptoms that contribute to infertility are irregular menstrual cycles, an excess of androgens, and chronic anovulation (Genazzani, Lanzoni and Riccieri 139).
Polycystic ovary syndrome is shortened to its acronym of PCOS by the medical community and the women who have been diagnosed with it. Polycystic ovary syndrome is predominant among reproductive women between the ages of 12 and 45 (Banning 635). Many women are not diagnosed with polycystic ovary syndrome until conception is desired.
To be diagnosed with polycystic ovary syndrome, women must meet two of three required criteria. Women will be tested for endocrine abnormalities in laboratory tests, radiologic abnormalities on ultrasound examinations, and clinical features, such as amenorrhea or central obesity. Additional etiologies must also be taken into consideration, and excluded, before the diagnosis of polycystic ovary syndrome can be made. Some of these exclusions are adrenal or ovarian tumors, congenital adrenal hyperplasia, and Cushing’s syndrome (Banning 638).
An example of abnormalities on endocrine tests would be an excess production of androgens. Androgens are hormones, made synthetically or by the testes, that promote the development of male sexual organs and male secondary sexual characteristics. The expression of excess androgens in women is typically hirsutism, acne, and female alopecia (hair loss or baldness) (Zacche, Caputo and Filippis 509).
Radiologic abnormalities on an ultrasound would show polycystic ovaries. Polycystic ovaries are the formation of clusters of pearl-sized cysts containing immature eggs in the ovaries. In healthy women, a follicle grows and at the time of ovulation, an egg is released into the Fallopian tube. In women with polycystic ovary syndrome, the development of the follicle is arrested and the egg does not burst forth. Therefore, the egg dies and the follicle becomes a cyst that remains in the ovary (Banning 635-636).
A clinical feature of polycystic ovary syndrome is anovulation. Anovulation is the absence of ovulation. Ovulation is the process in which the ovary releases an egg into the Fallopian tube. If an egg is not present to meet the sperm in the Fallopian tube, then conception cannot take place. If a woman is not ovulating then she is not able to conceive. ...

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