Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE) is a long-lasting, autoimmune disease which can affect nearly any part of one’s body. In normal circumstances the body is secured by the immune system. As soon as the immune system identifies harmful foreign substances the body’s usual defense would be for the immune system to abolish the antigens. In lupus suffering patients, the immune system doesn’t have the ability to differentiate regular antibodies from intruders. Lupus is when the body overreacts to a foreign stimulus and creates too many antibodies toward its own body tissue. Hence, Lupus is referred to as an autoimmune disorder. SLE causes inflammation to the joints, organs and tissue. The inflammation is identified as soreness, warmth, swelling and redness.
There are many sgns and symptoms of SLE. Symptoms of lupus tend to vary from each person and range from mild to severe, usually affecting persons between ages 15 and 50. The most commonly reported indicators are joint discomfort, skin rash, stiffness as well as fever. Patients with lupus may experience symptoms that suddenly worsen or appears unexpectedly. Most patients with SLE haves flashes, which signs rapidly appear and worsen and then relax for a long period of time. Nonetheless, the most frequent complaints include lethargy, aching or inflamed joints, fever, skin outbreaks and kidney issues. The butterfly rash, a red rash, is a noticeable sign of lupus and may appear on the face that spreads across the cheeks and nose. Protection against UV rays is very important because many suffer from photosensitivity. Other symptoms consist of brittle hair, mouth ulcers, chest pain, anemia, dry eyes, bruising, menstrual irregularities and paleness. Patients also report headaches, dizziness, seizures, and depression.
The history of lupus is very thought-provoking. Lupus is Latin word meaning wolf. It refers to the facial lesions that ranges across the nose and upper cheekbones and was to bear a resemblance to one being bitten or scratched by a wolf. Erythematosus is a word from Greek meaning red and refers to the pigment of the rash.
Lupus is a chronic disease of unknown etiology that is very difficult to diagnosis and treat. Scientists do not know the reasoning why the irregular immune response but it is possibly a mix of genetics and environmental factors. Persons that acquire this condition may have a genetic susceptibility that is produced by ecological influences like sunshine, hormones or bacteria. Investigators approximate that 20-100 diverse inherited factors can make a person receptive to SLE.
Systemic Lupus Erythematosus is a very challenging malady to diagnosis. Before an analysis can be completed, three of eleven labortary standards must be met. Antinular antibody titer is the chief labortory examination used to diagnosis SLE. Patients with an antinuclear titer of 1:40 and characteristics of mutliple organ system involvement can be diagnosised with...