Not many people in the United States have come in contact with a disease called Leishmaniasis; however, in southern Europe and the tropics of the world this disease is a force to be reckoned with. Leishmania spp., also known more commonly as cutaneous leishmaniasis and visceral leishmaniasis, is a bacterium causing a parasitic disease either on the surface of the skin or within the body in internal organs. An experiment was conducted to see if leishmaniasis should be included in the CDC clinical category C for the definition of AIDS.
Leishmania spp. belongs to the archaebacteria and eubacteria kingdom. It is a bacterium causing a parasitic disease found in the ...view middle of the document...
Visceral leishmaniasis can also be a silent infection without any symptoms or signs. People who develop clinical evidence of infection have many symptoms including fever, weight loss, enlargement (swelling) of the spleen and liver, and abnormal blood tests.
Low blood counts, including a low red blood cell count (anemia), a low white blood cell count (leukopenia), and a low platelet count (thrombocytopenia) can also be signs and symptoms of this disease (Parasites - Leishmaniasis).
In the experiment titled Leishmaniasis as an opportunistic infection in HIV-infected patients: determinants of relapse and mortality in a collaborative study of 228 episodes in a Mediterreanean region, scientists aimed to answer the question, “Should Leishmaniasis be included in the CDC clinical category C for the definition of AIDS?” The aim of this study was to describe the clinical features and determinants for relapse and case-fatality of visceral leishmaniasis in HIV-infected patients from a Spanish Mediterranean area (Pasquau). A chart review was conducted in 16 hospitals in the autonomous communities of Valencia and Murcia (Spain). From 1988 to 2001, a total of 228 episodes of visceral leishmaniasis were diagnosed in 155 HIV-infected patients. HIV-infected patients with visceral leishmaniasis were presented with fever (76%), hepatomegaly (77%), splenomegaly (78%), and varying degrees of cytopenias (all terrible infections). Leishmania was detected in atypical sites in 22 (14%) patients. A total of 37 (24%) patients had a relapse of visceral leishmaniasis. A total of 86 (54%) patients died (Pasquau). The findings show that, in HIV-infected patients, visceral leishmaniasis occurs in late stages of HIV...