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Meloxicam, A Prescription Only Drug For Arthritis

1672 words - 7 pages

INTRODUCTION
In this essay I will be writing about Meloxicam which is a prescription only drug. I will dedicate a section for the contraindication and cautions, a section for metabolism and elimination and a section for the interactions of Meloxicam with other drugs. The formula for Meloxicam is C14H13N3O4S2. This drug is a long acting Non-Steroidal Anti-Inflammatory Drug (NSAID). It is used in order to treat arthritis, by decreasing the stiffness, inflammation (swelling) and soreness of the sufferer’s joints.
CONTRAINDICATION AND CAUTIONS
There’s an indication of the possible danger of Meloxicam in varying situations. For instance, the third trimester of a pregnancy (week commencing 28 and until delivery date), anyone under the age of sixteen years old, those who suffer from bleeding disorders such as Gastrointestinal bleeding and severe heart failure, as well as other conditions. When being treated with Meloxicam no other NSAID medications should be taken at the same time as this intensify toxicity levels, also the patient should not consume more than the maximum daily dose.
As mentioned above Meloxicam has gastrointestinal effects, for instance, bleeding (whether it is perforation or ulceration, it could be lethal. There could be symptoms as warnings or none at all, even if there is or isn't Gastrointestinal problems before.) There higher a risk of bleeding the higher the doses the patient takes if the patient has Ulcer history and in specific if the patient suffers from haemorrhage perforation also senior citizens. Those who fall under this category should start on the lowest dose accessible and combination therapy is preferred.
Meloxicam can affect Cardiovascular and Cerebrovascular. Patients who suffered from Hypertension and congestive heart failure should be monitored because fluid retention (fluid build-up) and oedema (excess watery fluid in tissues or cavities) been reported. Congestive heart failure is when the heart can't deliver enough pump action to sustain blood flow. Blood pressure should be monitored. High doses and long term treatment, possibly slightly increase Arterial Thrombotic risk (blood clot in vessel blocking blood flow), according to clinical trial and epidemiological data (statistical and research based data). Epidemiology literally means "the study of what is upon the people" [1].
Only after extreme and careful thought should those patients with the above conditions, the same applies to those suffering from cardiovascular disease. In rare cases, severe skin reactions (sometimes fatal) such as Exfoliative dermatitis; widespread scaling of skin, and toxic Epidermal Necrolysis; separation of top layer of skin from the bottom layers of skin (more serious case of Stevens-Johnson syndrome). Normally appears at the beginning of the treatment, Meloxicam should be discontinued then. 1. Meloxicam sometimes raises the levels of serum transaminase; which is a "group of enzymes that catalyze the interconversion of amino acids...

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