This website uses cookies to ensure you have the best experience. Learn more

Microbiome Essay

660 words - 3 pages

Turnbaugh et al. investigates the gut microbiome with its association with obesity by testing the gut microbiota using the caecum, and through the results, it is observed that the microbiota found within the gut is only partially responsible for obesity, along with the specific genotype, lifestyle and potentially other environmental factors. The study uses mice with a particular chosen genotype, either obese or lean, to sequence the microbiota to see what bacteria is present for the different mice, and the study uses germ-free mice to test the success and effect of microbiota transplantation. The study is hopeful to develop a way to understand why obesity occurs with relation to the gut microbiota by uncovering unknown ideas about the gut microbiota and its effects on mice that can be transferred to the human.
The conclusions reveal that the microbiota likely is a contributing factor in obesity, but there are other factors involved. The results show that there is a greater amount of Firmicutes in the obese mice than the lean mice. Additionally, it is observed in microbiota transplants that both obese donors and receivers, suggesting that the microbiota did not colonize the donor community within the two weeks before testing. The overall results suggest that the obese mice had increased food consumption due to a lack of leptin receptors, a hormone that helps to control energy balance. The change in energy balance in obese people does not seem to be contributed by the gut microbiota. The results suggest that further testing could be completed to understand the components leading to obesity. There are issues found within the paper that could alter the results of what was observed. First, although the mice have a specific genotype, each mouse is different. This will be more of an issue if the same study is completed on humans because there are different cultures and diets. The microbiome is only a contributing part to obesity, but if the...

Find Another Essay On Microbiome

Braces and Crohn's Disease Essay

1291 words - 5 pages brackets that are attached to the teeth and connected with a thin wire that is held to the braces with small, usually colorful, elastics. In a recent study, it was observed that the bacteria P. gingivalis, T. forsythia, and T. denticola were more prevalent in patients with braces and caused periodontitis. This study suggests that there is potentially a shift in the microbiome of their mouth when a patient receives orthodontic treatment. It is

The Functions of the Gut Microbiota

2010 words - 8 pages comprehension of nutrition on the human gut and health (25). Works Cited 1. Siezen R.J., Kleerebezem M. (2011). The human gut microbiome: Are we our enterotypes? Microb. Biotechnol, 4: 550–553. 2. Chung, H., Pamp, S. J., Hill, J. A., et al. (2012). Gut immune maturation depends on colonization with a host-specific microbiota. Cell, 149(7), 1578-1593. 3. Wu GD, Chen J, Hoffmann C., et al. (2011). Linking long-term dietary patterns with gut

Benefit of Metagenomics

2120 words - 9 pages genomic information is obtained microbiologists can better assess the genomes already discovered, and develop a better understanding of the roots of microbial diversity in general and the effects it can have on the world around it. There are multiple projects currently in progress that are attempting to use metagenomics to sequence entire microbial genomes in certain habitats, each with an underlying purpose. The Human Microbiome Project seeks

Can you find antibiotics in plants?

1028 words - 5 pages February 6, 2014, from http://www.livestrong.com/article/93737-natural-antibiotics-plants/ Zimmer, C. (2013, June 18). Tending the Body’s Microbial Garden. Tending the Body’s Microbial Garden. Retrieved February 6, 2014, from http://www.nytimes.com/2012/06/19/science/studies-of-human-microbiome-yield-new-insights.html?pagewanted=all&_r=1& Cowan, M. (1999, October 12). Plant Products as Antimicrobial Agents. PMC US library of medicine. Retrieved

Write the advantages and disadvantages of the GATTACA - physics - essay

665 words - 3 pages found , for example, that prolonged use of antibiotics during adulthood was associated with a greater risk of developing precancerous polyps, possibly because antibiotics can alter the makeup of the gut microbiome. Scientists are also exploring whether the colorectal cancers emerging in younger adults are different from those seen in older people — and

The Community of Microorganisms that Reside in the Epithelia of Humans

1150 words - 5 pages There is a large number of species of microbes found on the human body. This bacterial organism are found in the skin, mouth, or nose. This lab consisted of the collection of skin bacterial organisms and amplification of the 16s rRNA to construct a small molecular phylogeny of the human body microbiome, or the community of microorganisms that reside in the epithelia of humans. This information could only be acquired through processes such as DNA

The Earlier Response of Differentiated H9C2 Cells

1206 words - 5 pages et al reported a non significant increase of Proteobacteria in blood microbiota of cardiovascular disease (CVD) patients (Amar et al., 2013). In our previous study, we demonstrated the abundance of Pseudomonadaceae family in the blood microbiome of CVD patients (Rajendhran et al., 2013). P. aeruginosa can invade and injure blood vessels (Plotkowski et al., 1994). Flagellin and endotoxin from the cell wall of Pseudomonas species can induce cardiac

Gut Bacteria of Breastfed vs Bottle Fed Infants

1241 words - 5 pages & Wold, 2009). The differences in gut bacteria between C section and vaginally delivered children could be seen as long as one year of age. There is some suggestion that the gut bacteria of C section born babies more closely match that of the hospital instead of the mother’s microbiome. Infants born in poor and unsanitary conditions, like those born in under or poorly developed countries, establish colonies of E. coli, Enterococci, and lactobacilli

The Negative Effects of Genetically Modified Foods

1579 words - 7 pages : 10.1111/j.1467-7652.2007.00300.x Mesnage R., Clair E., Gress S., Then C., Székács A., Séralini G.-E "GM-Free Cymru." CRUCIAL PAPER 27: BT Proteins Are Toxic to Human Cells. Article first published online: 15 FEB 2012, Journal of Applied Toxicology Samsel, A.; Seneff, S. Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases. Entropy 2013, 15, 1416- 1463.

The Dangers of Genetically Modified Organisms (GMO)

3835 words - 15 pages -info.com/gmo-infertility.html Samsel, A., & Seneff, S. (2013, April 10). Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases. Retrieved December 27, 2013, from GMOevidence: http://gmoevidence.com/wp-content/uploads/2013/04/GlyModern-diseaseSamsel-Seneff-13-1.pdf Shahan, Z. (n.d.). Genetically Modified Foods Causing Animal Miscarriages, but Who Cares? Retrieved December

When the Bubble Burst

1539 words - 6 pages By the time I arrived state side from my second tour in the Middle East the housing bubble had already burst. I noticed a drastic change in the way that many of my friends and family were living. Several of my friends that worked in real estate had sold their boats and seconds houses. My own stock portfolio had lost a third of its value. My sister and her husband had defaulted on their home mortgage leaving them scrambling for a place to live. I

Similar Essays

Human Microbiome Essay

947 words - 4 pages Human Microbiome Project and Cancer "Cancer is a leading cause of death worldwide and accounted for 7.6 million deaths… Deaths from cancer worldwide are projected to continue rising, with an estimated 13.1 million deaths in 2030," (World Health Organization). Cancer is a disease where the cells have gone completely out of control. Their DNA has been mutated, in which their instructions to undergo apoptosis ceases. Cancer is harmful to the

Skin Microbiome Essay

1648 words - 7 pages THE HUMAN SKIN MICROBIOME Throughout the millions of years of human evolution, humans and microorganisms have evolved side by side. In fact the cells of microorganisms out number human cells in the body. Some of the relationships between these microorganisms are mutualistic like Lactobacillus that helps the human body digest lactose and competes with pathogenic bacteria which boosts the immune system. Other bacteria that

The Human Microbiome And Gut Microbiome And Obesity

792 words - 4 pages obesity is the gut microbiome. The gut microbiome plays a key role in obesity in which the gut microbiome regulate host metabolic inflammation, and certain type and amount of gut microbiome in human are directly relate to obesity. The human gut contains a huge diversity of bacteria and the microbiota, which is crucially important for maintaining human health. According to Greiner et al, the gut microbiome plays an important role as a regulator to

Anat 409: Summary Ii On The Microbiome Anatomy Assignment

895 words - 4 pages Summary II: Papers 6-10 The microbiome changes in microbial number and diversity from birth to death and increases in microbial number and diversity ranging from the stomach to the colon. The normal microbiota is associated with normal behaviour while dysbiosis, in stress and disease, is associated with abnormal behaviour. Through the brain-gut axis (BGA), there is bidirectional communication where the hypothalamic-pituitary axis (HPA