This website uses cookies to ensure you have the best experience. Learn more

The Effects Of Micro Rna On Health

697 words - 3 pages

3. MicroRNA-155
MicroRNA-155 is highly expressed in lung cancer, breast cancer, acute myelogenous leukemia (AML), Hodgkin’s disease, pediatric Burkitt’s lymphoma, pancreatic tumour and chronic lymphocytic leukaemia (CLL) (33). MicroRNA-155 has an essential function in regulating T helper cell differentiation and the germinal centre reaction to produce an optimal T cell dependent antibody response, at least in part, by regulating cytokine production (34). MicroRNA-155 also participates in other cellular processes such as interferon production in natural killer cells, lymphoma cell motility, dendritic cell differentiation and function and skeletal muscle differentiation etc. (35, 36)
4. MicroRNA-17-92
MicroRNA-17 – 92 is intensified and overexpressed in hematopoietic malignancies (37). Myc induces the expression of this microRNA cluster and the mature microRNAs expressed repress E2F transcription factors in a complex network and controls cell cycle progression and apoptosis (38). These microRNAs can modulate the expression of many different molecules involved in several cellular processes including apoptosis, tumour suppression, cell cycle and cytokine signalling (39).
5. MicroRNA-21
MicroRNA-21 is overexpressed in most tumour types including brain, colon, lung, breast, pancreatic, cervical and oesophageal cancers. Inhibition of microRNA-21 results in growth inhibition and up regulation of the cell cycle inhibitor P 21 (40). P 21 is a cyclin dependent kinase inhibitor that regulates the cell cycle. Meng et al. showed that inhibition of microRNA-21 in liver cancer cells decreased tumour cell migration, proliferation and cell invasion (41).
Secondly we’ll look at Diabetes – another silent killer,
MicroRNA and Diabetes

Over 2.2 million people with diabetes have been recognized in the UK by the Diabetic Retinopathy Screening Programme in 2013. The incidence of Type II diabetes is increasing in every country especially in developing countries such as India and China (42). This is mainly due to immobility and obesity (42). By 2030, the world incidence of diabetes is expected to reach 366 million (42, 43). Diabetes is a common lifelong health condition.
In Type I diabetes, pancreatic beta cells do not produce insulin and in Type II, cells do not recognise the peptide hormone, insulin (104). The...

Find Another Essay On The Effects of MicroRNA on Health

Negative Effects of Smoking on Human Health and the Economy

1934 words - 8 pages Moreover, smoking particularly adversely affects women's reproductive health, and smoke exposure on children has had detrimental and some sometimes fatal effects on children. Many studies have examined and outlined the adverse effects of maternal smoking on both the mother as well as on the baby and/or infant ( Hofhuis, de Jongste, & Merkus, 2003 & Woolbright 1994). Many states such as Alabama required documentation on birth certificates of

The Effects of Unhealthy Human Sexuality on Whole Person Health

2598 words - 10 pages , more than four times the risk of early sexual intercourse, and two and a half more times higher risk of early pregnancy when compared to women in intact families.” (Quinlan 376-390) Apparently, there are physical as well as emotional effects brought on by a young girl’s parents to being involved and committed to one another. Fathers need to be more intentional about the health and well-being of their daughters when circumstances cause him to

The Effects of Divorce on Children's Mental Health

1458 words - 6 pages Considering that over 45 percent of marriages today end in divorce, it is crucial to understand recent research regarding the positive and negative effects of divorce on children’s mental health. Studies have shown that although children of broken homes generally have more adjustment difficulties than children of intact families, the distinction between these two groups appears to be much less significant than previously assumed (1). In the case

The Health Effects of Smoking

679 words - 3 pages The health effects of smoking are horribly destructive and in many cases, deadly. The ingredients in cigarettes affect everything from the internal functioning of organs to the efficiency of the body’s immune system. The chemicals in cigarette smoke are inhaled into the lungs and then travel throughout the body, causing damage in numerous ways. Smoking harms nearly every organ of the body and diminishes a person’s overall health. Cigarette

Detrimental Effects of Smoking on Your Health

1189 words - 5 pages literally be the difference between life and death. The detrimental effects of smoking to your health, the carcinogenic materials in cigarettes and the smoke byproduct, and the surprising negative impact on one’s appearance are compelling reasons to never engage in smoking. Most people don’t realize how many poisons, toxic metals, and even radioactive material that are in and/or come from cigarettes and the cigarette smoke byproduct. “Cigarette

Health Effects on Humans of Fracking

2237 words - 9 pages Human Health and Hydraulic Fracturing Current research, in the field of public health, is looking at the adverse health effects of hydraulic fracturing on community members. This research is focused on looking for evidence-based research in processes, procedures, materials and cleanup from drilling and running a well. In recent years, several states such as Maryland and New York, have called for special advisory commissions to examine the

Effects of Caffeine on Human Health

1269 words - 5 pages which results in the increase of heart rate, dilation of pupils and many other effects. Overall, the secretion of this hormone has the ability to heighten energy and attentiveness. Besides that, similar to drugs like cocaine and methamphetamine, the consumption of caffeine increases the production of the neurotransmitter called dopamine. The manipulation of dopamine levels has ability to cause positive effect on moods and contributes conscious body

Effects of Employment on Perceived Health

1286 words - 6 pages Sample and Delivery HINTS data collection is conducted every 2-3 years in order to provide trends in the areas of health and cancer interests. In HINTS, the eligibility rate is quite high because all adults are eligible (only households with no adults are ineligible). HINTS strives to: provide updates on changing patterns, needs, and information opportunities in health; identify changing health communications trends and practices; assess cancer

The Effects Agent Orange Produced on Health

2155 words - 9 pages this toxin were sprayed. (Department of Preventive Medicine 1) It affected the Vietnamese and the American troops who were fighting in the same jungle. Little did the United States military know the effects of this dangerous herbicide. It caused many long-term complications, including health problems for the veterans, birth defects, and contaminated grounds. Therefore, it was wrong of the United States to spray such a dangerous herbicide without

Effects of mental health on the family - hampton university/ sociology of the family - essay

3369 words - 14 pages , Pratt, Thompson, Dhingra, McKnight-Eily, Harrison & Safran, 2011). According to the World Health Organization (WHO), mental health illness make a significant contribution to the burden of diseases worldwide (Prince, Patel, Saxena, Maj, Maselko, Phillips & Rahman, 2007). Mental health illnesses can affect a person at any point in their life possibly causing long-term disability and dependency on the family (Prince et. al., 2007). The family is a

The Effects of Cyber Bullying on the Mental Health of Middle School-aged Youth

1901 words - 8 pages . With the constant physical, emotional, and environmental changes going on, the risk of cyberbullying amongst middle school students increases (Kowalski and Limber, 2007). Looking at research, it is evident that there is a lack of research on cyber bullying and the multiple effects on mental health with Tarrant County middle school-aged children. In order to assist middle school-aged youth in the prevention of cyber bullying and protection of mental

Similar Essays

The Effects Of Forgiveness On Mental Health

2471 words - 10 pages Sedikides 2002). This may cause them difficulty for them to forgive as they expect others to make amends first because of their characteristics fail to empathise (Maltby, Day and Mackaskill 2007). However it has been questioned on the importance of empathy as research has shown sometimes those who forgive do not feel empathy towards the offender (Flanigan 1992). It could be suggested to research into mental health effects of forgiveness without

The Effects Of Exercise On Mental Health

1921 words - 8 pages exercise being effective in reducing self-reported depressive symptoms, Diaz and Motta (2008) and Motta, Kuligowski, and Marino (2010) looked at the positive effects of exercise on depression, anxiety and PTSD. The theory of exercise’s positive effect on mental health has heavily been focused on depression and anxiety, but PTSD is becoming a newer area of research as it contains not only depressive and anxiety based symptoms as well as other

Effects Of The Recession On Health Care

663 words - 3 pages who have health insurance. In some health care facilities in the United States, doctors are unable to perform surgery on persons who do not have an adequate insurance coverage that can cover the expenses of the surgery. In this way the individual is left in a state of poor health. Persons constantly live in the fear of not knowing whether or not their loved ones would ever become seriously ill. This is due to the monopolies of the government

Negative Effects Of Smoking On Human Health And The Economy

1277 words - 6 pages Smoking Initiation. Pediatrics, 104(4), 918- 924. Warner, K., Hodgson, T., & Carroll, C. (1999). Medical Costs of Smoking in the United States: Estimates, Their Validity, and Their Implications. Tobacco Control, 8(3), 290-300. Women and Tobacco Use - American Lung Association. (n.d.). American Lung Association. Retrieved March 19, 2014, from figures/women-and-tobacco-use.html Woolbright, L. A. (1994). The Effects of Maternal Smoking on Infant Health. Population Research and Policy Review, 13(3), 327-339.