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Never Let Me Go & Innovations To Organ Regeneration

1014 words - 5 pages

Organ donation is becoming a global dilemma, the ratio between donor organs and the demand for them is broadening. In the United States alone, 18 out of every 100,000 patients die every day waiting for an organ. Furthermore, both the donor and the receiver must be compatible with each other for a successful transplantation to occur. Both donor and receiver have to be compatible such as by blood type to relieve the risk of rejection. In the novel “Never Let Me Go” by Kazuo Ishiguro society has found a way to surpass this issue and make organ transplantations successful without causing harm to the patient. “Your lives are set out for you… before you’re middle aged you will start donating ...view middle of the document...

The scaffold was created and seeded with the patient’s own stem cells and left to grow in a bioreactor which is a machine that simulates the internal environment of the human body. The end result was a trachea that was compatible with the patient, which saved the patient’s life. However, this method like any technology has its limitations.
The synthesis of organs containing many blood vessels such as the heart is problematic as the scaffold must contain the appropriate framework of blood vessels. The modern method of obtaining such scaffolds is to wash off the cells of previously existing donor organs such as a donor heart. The process begins with the injection of cleaning detergents through the Aorta of the heart, which gradually dissolves away the donor’s cells. Afterwards, the remaining scaffold is injected with a solution of the patients stem cells that differentiate to those found in the heart ultimately, relieving the risk of rejection. The heart is still not able to beat on its own and thus must be stimulated through an electrical signal to intestate muscle contractions. However, this does not compensate the fact that the ratio between supply and demand of organ transplants are enlarging.
“How can you ask such a world that has come to regard cancer as curable, how can you ask such a world to put away such a cure, to back to the dark days?” (Ishiguro, 263). The dystopian society exemplified in the novel has come to accept harvesting organs from clones as it solves many of the outstanding issues of organ transplantation. The society has become so accustomed to the many benefits that these clones provide that they are willing to take the lives of the clones to save their own. A plausible solution to attaining scaffolds with the correct framework of blood vessels is the utilization of chemical compounds termed growth factors. Scientists depend on the natural ability of cells to form these interior frameworks of blood vessels and thus stimulate angiogenesis through the use of these growth factors. Nevertheless, these chemical compounds are extremely expensive to...

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