This website uses cookies to ensure you have the best experience. Learn more

Pathophysiology Of Diabetes Mellitus Essay

2345 words - 10 pages

Michael Snavely
MED 2056, PTW
Diabetes Mellitus
Melissa Garcia

Pathophysiology of Diabetes Mellitus
Diabetes Mellitus is a group of metabolic diseases. The body is unable to produce or absorb sufficient amounts of insulin. This causes elevated levels of glucose in the blood. The pancreas normally produces insulin which regulates the level of glucose in the blood as 1)well as how it's used. "Glucose is vital to your health because it's an important source of energy for the cells that make up your muscles and tissues. It's also your brain's main source of fuel" ( 2014).

The endocrine pancreas is filled with the islets of Langerhan. These islets, or regions of the pancreas, are "clusters of cells, which each 'islet' containing 3,000 to 4,000 cells. Scientists estimate there are 1 million islets in a healthy, adult pancreas"( 2014). They are beta cells (endocrine or hormone-producing) cells and are named after the discoverer, German pathologist Langerhans in 1869. Normally, when glucose is ingested, these beta cells produce insulin. "Glucose goes into the bloodstream and to various organs. In the liver, the liver cell has a little insulin receptor. The insulin binds with it and the cell increases the glucose transporter so glucose is then taken up by the cell" (
of DiabetesMellitus). If a person does not have enough insulin, glucose cannot enter body cells, and this results in blood glucose levels rising. Symptoms of hyperglycemia can then occur, and diabetes mellitus may develop.
"The way that insulin fails determines how a diabetic is classified" (

Compare and Contrast
Possible Causes of Type 1 and Type 2 Diabetes Mellitus

There are many possible causes of Type 1 and Type 2 Diabetes Mellitus. They include environmental and genetic. Both Type 1 and Type 2 are chronic conditions.
Type 1
"In Type 1 Diabetes, the pancreas does not produce insulin" ( 2014). University of Maryland Medical Center) Scientists are still working on the exact cause of type 1. When there's no insulin, glucose cannot get into the cells. Sugar then builds up in your bloodstream which can result in life-threatening complications. In Type 1, beta cells in the pancreas are destroyed. Once the beta cells are gone, there is no insulin produced. Why does this happen?

One environmental explanation may be that it is due to an auto-immune response that progresses pretty quickly. There may be exposure to a virus. Dr. Andrew Wolf, of YouTube's Pathology of Diabetes states that the immune system creates antibodies to the virus' proteins and thus the virus is destroyed. However, the immune system, goes on to also destroy the beta cells in the pancreas. Other environmental factors could include cold weather because Type 1 develops more often in winter than summer and is more common in places with cold...

Find Another Essay On Pathophysiology of Diabetes Mellitus

Management of Hospitalized Patient With Diabetes Mellitus

2806 words - 11 pages Mr. Brown is a 45 year old male who has been diagnosed with type 2 diabetes mellitus (T2DM), peripheral arterial disease,(PAD), and hypertension (HTN). Mr. Brown requires immediate intra venous therapy of normal saline to re-hydrate and correct his electrolyte imbalance. Mr. Brown was admitted to the ward following a revascularization procedure on his anterior lower right leg, and has a history of Hyperosmolar Hyperglycaemic Nonketotic Syndrome

Liraglutide: Novel treatment of Type 2 Diabetes Mellitus

1398 words - 6 pages medications and assisting patients in reducing weight. Liraglutide: Novel treatment of Type 2 Diabetes Mellitus Type 2 Diabetes is rapidly becoming the top health concerns in the United States and a major contributor to health care spending and disability. There are an estimated 22.3 million people in the United States diagnosed with diabetes, this represents 7% of our population (American Diabetes Association [ADA], 2013, p. 1038) The American

Liraglutide: Novel treatment of Type 2 Diabetes Mellitus

2208 words - 9 pages . (2014). Lexicomp (2.0.1(165)) [Mobile application software]. Retrieved from Micale, S. J., Kane, M. P., & Hogan, E. (2013). Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus. Case Reports in Pediatrics, 2013. Retrieved from Novo Nordisk Inc. (2013). Victoza liraglutide (rDNA origin) injection. Retrieved from

Liraglutide: Novel treatment of Type 2 Diabetes Mellitus

2135 words - 9 pages application software]. Retrieved from Micale, S. J., Kane, M. P., & Hogan, E. (2013). Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus. Case Reports in Pediatrics, 2013. Retrieved from Novo Nordisk Inc. (2013). Victoza liraglutide (rDNA origin) injection. Retrieved from Robinson, M., & Wynne, A. L

Metabolic Control of Adults With Type 2 Diabetes Mellitus

1153 words - 5 pages This paper is to critique a study conducted on the metabolic control of adults with type 2 diabetes mellitus. This one year study examines the impact of education and counseling on the metabolic control specifically in the Mexican population. Burns and Grove (2009) describe sampling as “a process of selecting subjects, events, behavior, or elements for participation in a study”. In this study, the researchers obtained a sample of the

Coexistence of Autoimmune Disease with Type I Diabetes Mellitus in Libyan Patients

2251 words - 10 pages measured for 748 patients. The venous blood samples were taken from all the subjects in the morning after fasting overnight while TPOAb and TGAb level were measured abroad. 101 of patients with type1 diabetes mellitus were included in this study were investigated for celiac disease and Addison disease. Both diseases were diagnosed abroad. Celiac disease patients have been diagnosed by finding a positive anti-tissue transglutaminase (TTG) test and

The author of this essay will be discussing a patient with type 2 Diabetes Mellitus

3083 words - 12 pages IntroductionThe author of this essay will be discussing a patient with type 2 Diabetes Mellitus and will also be discussing the nursing care that will be received by the patient following a hypoglycaemic attack.The patient being described is a fictitious seventy year old lady called Mabel Gordon; she lives in a flat in a city centre with her husband Bert. Mabel has had type 2 diabetes for years which has been poorly controlled by medication and

The Role of DPP-4 Inhibitors in Type 2 Diabetes Mellitus

2600 words - 11 pages document, the pharmacology, clinical efficacy, and incidence of adverse effects will be reviewed in an attempt to target a patient population that would benefit the most from treatment with DPP-4 inhibitors. The role of DPP-4 inhibitors in type 2 diabetes mellitus management INTRODUCTION Type 2 diabetes mellitus is a chronic, progressive disease that currently affects approximately 285 million people worldwide and is estimated to affect 430

Compare and Contrast Pancreas Releated Disorders

582 words - 3 pages Type 2 would be Obesity or being overweight meaning that they lack of exercise, and unhealthy or poor nutrition. “Diabetes has long been linked to obesity and being overweight.” (WebMD, 2005-2008, Discuss pathophysiology of Type I and Type II DM Type 1 Diabetes Mellitus, a triggering event, possibly a viral infection leading to production of autoantibodies that kills the bodies beta cells

Diabetes Mellitus

1485 words - 6 pages 1. Discuss the pathophysiology of Diabetes Mellitus. Diabetes Mellitus is a chronic condition in which the body has the inability to produce insulin or react normally to insulin. The pathophysiology of diabetes mellitus is extremely complex, as diabetes mellitus is characterized by different types but share common symptoms and complications. Diabetes mellitus is classified in two types: Type 1 and type 2 diabetes. Although the

Diabetes Mellitus

1738 words - 7 pages Diabetes mellitus (DM) or simply diabetes, is a chronic health condition in which the body either fails to produce the amount of insulin needed or it responds inadequately to the insulin secreted by the pancreas. The three primary types of diabetes are: Diabetes Type 1 and 2, and during some pregnancies, Gestational diabetes. The cliché for all three types of diabetes is high glucose blood levels or hyperglycemia. The pathophysiology of all

Similar Essays

Molecular Mechanisms Of Diabetes Mellitus Essay

1793 words - 8 pages cells associated and functioning in the kidneys, ultimately leading to stages of renal dysfunction to progression of renal failure. Both type 1 and 2 diabetes mellitus are obviously diverse in pathology and in the mechanisms in which the metabolic disorder proceeds, however, similarly, the physiological changes that result from diabetes impacts various tissues of the renal system, including the glomerulus, tubointerstitium and vasculature

Gerontologic Considerations Of Diabetes Mellitus Essay

1951 words - 8 pages Gerontologic Considerations of Diabetes Mellitus According to the Department of Health and Human Services (2011), 18.5 % of the United States population is over the age of 60 years. Of these, 10.9 million (26.9%) are diagnosed with diabetes mellitus (ADA, 2011.) In Lewis and associates’ text book on Medical- Surgical nursing, Lewis states that the incidence of diabetes mellitus (DM) increases with age (Lewis, Dirksen, Heitkemper, Bucher, and

A Study Of Diabetes Mellitus Essay

2822 words - 11 pages , there is no known cure for diabetes.Diabetes MellitusDiabetes DefinedDiabetes Mellitus is a chronic disease where the blood in the body contains a high sugar level. This disease is caused by the body's inability to use insulin properly, or the inability to manufacture insulin altogether. There are times when it can be caused by both factors. "Diabetes is the leading cause of blindness, kidney failure, and leg amputations. In fact, it is the third

The General Symptoms Of Diabetes Mellitus

3268 words - 13 pages A person suffer from diabetes mellitus has high blood sugar if left untreated. Explain diabetes, blindness and kidney failure Diabetes Definition and diagnostic criteria for diabetes mellitus. Nowadays many people, especially in the developed nations though not solely, suffer from diabetes. American Diabetes Association (2014) had studied that diabetes mellitus is a group of metabolic disorders and which reveal themselves by causing