II. Background Information
Polycystic kidney disease is a genetic disease that could be passed from generation to generation.. Many cysts forming the kidneys, causing them to become enlarged. Round cysts contain of water-like fluid and they are noncancerous, could grow inside the liver and spread in other parts of the body.
Before getting into more close details about the PDK, it is important to understand what function kidney does and why they are an essential organs in human’s body. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. Kidneys function is to filter wastes and extra fluid from the blood to form urine. Moreover, they regulate amounts of other vital substances in the body.
Growing cysts can profoundly enlarge the kidneys thus changing their normal shape, structure and prevent them from proper working. If the disease is not being noticed in a right time the cysts might spread and this might lead to reduced kidney function and later, kidney failure.
Richard Bright, a British physician and medical researcher was the first to discover this disease. He also participated in studying other kidney diseases. Bright was born on September 28th, 1789 in Bristol. He grew up in a wealthy family. He worked together with two, most prominent figures of British medicine at that time, Thomas Hodgkin and Thomas Addison and that lead to many different discoveries about kidney related diseases (1820). They published numerous works and research papers that later lead to the discovery of the treatments of the diseases. All those researches provided him with enough information to come up with the symptoms of polycystic kidney disease. This disease was also named after the scientist, as Bright’s disease.
He is also known as the father of nephrology because of his big input in the medical research. *(Nephrology is a specialty of medicine and pediatrics that concerns itself with the study of normal kidney function, kidney problems, and the treatment of kidney problems).
Today, the specific cure to heal a person from the PDK is not found. The main solution is dialysis or the kidney transplantation however, it does not always solve the problem because the cysts might renew or the transplantation might not be successful. Every patient has to make frequent appointments to the nephrologists to check on the disease and follow its development. Visits are important part of the treatment. In that way the chance to control symptoms and prevent complications is much bigger.
Autosomal dominant PKD is the most commonly inherited disease in the United States. It is passed from one of the parent that has the disease. If one parent has autosomal dominant PKD, each child has a 50/50 chance of inheriting the disease.
Famous People with this disease:
Erma Bombeck - American humorist. She became popular for her newspaper article that described suburban home life during 1960s-1990s. Bombeck...