Pyogenic infections are characterized by severe local inflammation, usually with pus development. It’s an incursion by and growth of pathogenic microorganism in a bodily part or tissue, which may produce succeeding tissue injury and development to overt disease through a variety of cellular or toxic mechanisms, generally caused by one of the pigeons bacteria. Infectious microorganisms such as Staphylococcus, Streptococcus, Neisseria, Klebsiella, Proteus, Pseudomonas (Sarala et al., 2010), Escherichia coli, Salmonella typhi, Mycobacterium tuberculosis (Singh et al., 2013) and some other species of pathogenic bacteria usually produce pus. This is usually a source of infection to others and the transmission can be either due to direct contact with through fomities. To cure the problem antibiotic is main options. The choice of an effective antimicrobial agent for a microbial infection requires awareness of the potential microbial pathogen, an understanding of the pathophysiology of the infectious process and an understanding of the pharmacology and pharmacokinetics of the intended therapeutic agents (Kelwin, 1999).
This study was aimed to isolate and identify the bacteria from the clinical pus samples obtained from the suspected patient with pyogenic infection and to detect the drugs of choice against the infection and in addition this study was carried out to determine the socioeconomic characters and pyogenic infection related characters associated with pathogenic infection among patients in a tertiary care center in Salem, TamilNadu, India.
Goswami et al. (2011) reported that predominant organisms isolated from wounds were Staphylococcus aureus 48 (26.23%) Klebsiella pneumoniae 38 (20.77%), Pseudomonas aeruginosa 37 (20.22%), and Escherichia coli 29 (15.85%) in at a tertiary care hospital in Gujarat, India. In the present study, the S. aureus was isolated in the maximum percentage (27.60%), followed by E. coli (20.70%), P. aeruginosa (17.20%), Klebsiella spp. and Polymicrobial infection (10.30%) and Proteus spp. and no growth was noticed in 6.9% of patients. The similar findings were observed in the studies done previously (Abu Hanifah, 1990 ; Surucuoglu et al., 2005)
In the study from the Tertiary Care Center in South-Western Nigeria, a total of 386 surgical patients were recruited into the study, 198 (51.3%) were males and 188 (48.7%) were females (Amoran et al., 2013). In the present study the highest incidence was observed in male patients (69%) than female (31%) with the pyogenic infection. Thus it could be inferred that males were more prone to operative wound infection. This might be due to personal behaviors such as Cigarette smoking, alcohol consumption etc. Cigarette smoking has been reported to have an impact on wound healing through impairment of tissue oxygenation and local hypoxia via vasoconstriction (Jone, Tripleff, 1992). S. aureus infection was occurred in male patients at maximum followed by P....