Review Analysis

749 words - 3 pages

Review Analysis and Evaluation

Importance of careful assessment of oral cavity for suspicious lesions for early detection of multiple myeloma.1

Article title: “The multiple oral presentations of multiple myeloma”.1
Bibliographic information: Richard C. Cardoso & Peter J. Gerngross & Theresa M. Hofstede & Donna M. Weber & Mark S. Chambers. Support Care Cancer (2014) 22:259–267 DOI 10.1007/s00520-013-1960-y.

The purpose of this study was:
1) “To show the varied oral presentations of multiple myeloma, illustrating the importance of carefully surveying the oral cavity for suspicious lesions that could ...view middle of the document...


Oral cavity lesions can be the first sign of relapse or succession of myeloma. Hence “members of the interdisciplinary oncology team should be aware of the various signs, symptoms, and treatment of multiple myeloma and its various presentations within the oral cavity”.1 It is essential to detect the oral manifestations of disease early and provide an effective coordination of the multidisciplinary team to treat patients.1

Commentary and Analysis

In this study individual cases are well defined with detail report on patient’s history, diagnosis of oral cavity lesions its location, various other symptoms of myeloma and its treatment are reported. Though specific subject selection criteria are not mentioned in the article, subject selection bias is not observed as cases reported in this article include both sexes, age range reported is broad from 31 to 70 years old the location and clinical appearance of each oral lesion were different. Author has reported and discussed each case and analyzed similarities and differences in all case reports. As per my opinion this study has following issues:
• The literature review was detailed explaining the etiology diagnosis and treatment of the disease however limited literature references were mentioned to support the conclusion that, Oral cavity lesions can be the first sign of relapse or succession of myeloma.1
• Only 5 cases were...

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