Roles Of Inflammation In Diseases Essay

1248 words - 5 pages

Inflammation could be defined as a medium by which the body tissues respond to all sorts of injury (Roitt, 1997). It is a defence mechanism against infection from injuries. Physical stimuli such as change in temperature, UV radiation, or skin irritation may cause release of inflammatory mediators such as cytokines that ensure the immune system provide suitable defence, chemokine that bring leukocytes to the inflammation site, eicosanoids, neuropeptides, etc. Inflammation could be acute or chronic. Acute inflammation is an immediate response to trauma; in which the body fights against foreign bodies and heal wounds. Inflammatory mediators are released from the cell, causing immune response. Vasolidation is another stage in acute inflammation; it causes increased blood flow and thus increases permeability of the blood vessels, which then result to the release of plasma protein into the affected tissues (Spector & Willoughby, 1963). It could be characterised by the redness, swelling and increased heat in the affected area. After vasolidation, the inflammatory cells penetrate the injured tissue because of increased permeability. Mast cells are responsible for releasing mediators like cytokine and chemokine that gets rid of dead cells and toxins. This is followed by the release of other important mediators by the endothelial cells. In order to make the inflammatory response effective, leukocytes, other mediators such as Leukotriene and Kinins. Ones chemokine brings leukocytes to the inflammation site, plasma proteins capable of destroying pathogenic agents are initiated, the injury begins to heal, and then acute inflammation ceases. Under normal conditions, the inflammatory response is deactivated by anti-inflammatory mechanisms to avoid prolonged inflammation, otherwise known as chronic inflammation. A good number of cells are fundamental in the initiation of inflammation. For example, mast cells, activation of mast cells release loads of mediators from its cytoplasm. These mediators brings all types of white blood cells such as monocytes which later become macrophages when they enter the tissue, dendritic cells that present antigens, neutrophils, all types of lymphocytes like B cells and T cells which brings about immune response, eosinophil and NK cells to the affected tissue. Stimulated mast cells produce a huge amount of TNF-α which activates all the cells involved in inflammation, to synthesize more on their own. Macrophage, monocytes, and activated platelets give rise to a cytokine called interleukin-1 (IL-1). It has paracrine effects such as activating T cells, initiates blood clotting cascade. It also has endocrine effects such as causing fever and increasing blood pressure. Other important cells in inflammation are bradykinins. They lower blood pressure and increase blood flow to tissues; they induce the capillaries to ease flow of blood content into target tissues. Their effect causes the typical redness and swelling in inflammation.

Find Another Essay On Roles of Inflammation in Diseases

Representation of Womens Roles in Society- Medea

1097 words - 4 pages Women’s lives are represented by the roles they either choose or have imposed on them. This is evident in the play Medea by Euripides through the characters of Medea and the nurse. During the time period which Medea is set women have very limited social power and no political power at all, although a women’s maternal and domestic power was respected in the privacy of the home, “Our lives depend on how his lordship feels”. The limited power

The Roles of Women in Different Societies

1298 words - 5 pages Women have been suffering discrimination in societies for years. They are considered inferior to men. In two different societies women’s have different roles, in Buddhist societies women are thought o have evolved socially than in Brahmanic societies . Women lead very different lives in Brahmanic and Buddhist societies. Buddhism was created by Buddha(565–485 BCE). The Buddha wanted equality. Instead of trying to overcome the strict caste system

Roles of Women in Vedic Culture

3513 words - 14 pages Roles of Women in Vedic Culture Vedic culture seems to have conflicting views regarding its attitude towards women, specifically its attitude towards a woman’s sexuality. This conflict can be seen by contrasting the ways in which women are treated in sacrificing rituals with how they are treated in a more intimate atmosphere, such as lovemaking, which is still often treated as a ritual in and of itself; ritual regarding fertility, love, and

Changes in the Roles of Women

967 words - 4 pages The roles of women changed drastically between 1950’s and 1970’s due to the political, economic, and social issues, but women’s lives also stayed close to the way they had always been. The lives of women changed in a plethora of ways throughout the years. “We believe that women can achieve such equality only by accepting to full the challenges and responsibilities they share with all other people in our society, as part of the decision-making

The Diverse Roles of Women in Movies

874 words - 3 pages The Diverse Roles of Women in Movies In society we have a lot of women actresses. Some tend to play the motherly type, some play the manipulator type and some even play the victims of abusive relationships. No matter what women seem to be coming up in the industry of movies in more ways than before. The three movies I have chosen to analyze in my critique are Heartbreakers, Baby Boy and Stepmom. These three movies all have women in them

Roles of Gods in The Iliad

1130 words - 5 pages “Nine days the arrows of god swept through the army.” (Homer, The Iliad, 1.61) The Iliad written by Homer portrayed the war between the Achaeans and the Trojans. In addition to the mortals fighting each other gods also intervened in the war between the two sides, the gods in The Iliad played very significant roles in the battles; they brought divine powers on to the mortal sides of the war, Greek gods embody many human characteristics, there

Extreme Roles of Women in Sports

1117 words - 4 pages Extreme Roles of Women in Sports Sports are so prevalent and popular these days that we often see them as symbolic of real-life issues and real-life drama. The football field can illustrate the battle between good and evil. The baseball pitcher, nearing retirement, can come back to give one last game and wow the crown one last time before gracefully surrendering the field. Isn't that what sports represent? The good guys (i.e. your baseball

Reduction of Diarrheal Diseases in Under-Five Children in Lagos, Nigeria

1189 words - 5 pages 75/1000 live births (DHS, 2010). Diarrhea accounts for 19% of all childhood mortality in Nigeria. This essay intends to discuss the reduction of diarrheal diseases in under-five children in Lagos, Nigeria. The essay will dwell to assess the epidemiological issues, including locally initiated data search, ƒthe chosen interventions and the implementation strategies to avert under-five children mortality caused by diarrheal diseases. Assessing

Role of Metabolites in Diagnosing Chronic and Infectious Diseases and the Efficacy of Therapeutic Interventions

684 words - 3 pages These scenarios share the critical need to develop noninvasive, low cost techniques that can help make critical decisions that impact everything from health, quality of life, costs, and public health policy. There has been recent interest in understanding the role that metabolites may play in diagnosing chronic and infectious diseases and the efficacy of therapeutic interventions. Since the metabolites represent the current state of the

Novel Approaches in Tissue Engineering and Regenerative Medicine Reducing the Incidence of Cardiovascular Diseases

1282 words - 5 pages Cardiovascular diseases (CVD) are a growing cause of concern globally, mainly due to sedentary lifestyle encouraged by technology. According to statistics obtained from the World Health Organization (WHO), CVDs are the primary cause of deaths worldwide. It is estimated that more people die from CVDs annually than from any other disease. The WHO further reports that in 2004, CVD was responsible for 17.1 million deaths globally. This represented

Knowledge and Perceived Risk of Major Diseases in Middle Aged and Older Women

2663 words - 11 pages Knowledge and Perceived Risk of Major Diseases in Middle Aged and Older Women The American Psychological Association Journal Article this paper is based on focuses on the knowledge of health related risks and behaviors of middle age and older age women, and specifically women's "knowledge of perceived risk of major disease" (Wilcox & Stefanick, 1999). A link between lifestyle and chronic disease in old age has been established. In

Similar Essays

Adiponectin: A Novel Indicator Of Malnutrition And Inflammation In Hemodialysis Patients.

2384 words - 10 pages considered to be the main cause of malnutrition in these patients (2). Adiponectin is a cytokine which is exclusively produced by adipose tissue and has multiple roles in glucose and lipid metabolism, insulin resistance and inflammation (3). Generally, adiponectin has an inverse relationship with the degree of adiposity (4). Serum levels of adiponectin were reported to be two times higher in hemodialysis patients than general population (5). Moreover

Roles Of Women In Antigone Essay

2511 words - 10 pages Roles of Women in the Greek Tragedy Antigone Despite the male dominant society of Ancient Greece, the women in Sophocles’ play Antigone all express capabilities of powerful influence and each individually possess unique characteristics, showing both similarities and contrasts. The women in the play are a pivotal aspect that keeps the plot moving and ultimately leads to the catharsis of this tragedy. Beginning from the argument between Antigone

Pathway Reconstruction Of Airway Remodeling In Chronic Lung Diseases

2526 words - 10 pages hyper-secretion is a major pathophysiologic feature in chronic inflammatory airway diseases. Trefoil Factor3 (TFF3) is one of starter points in the airway remodeling pathway as shown in figure 3. Trefoil family has three homologous (TFF1, TFF2, and TFF3) [43,44]. Although the exact function of TFF3 in the respiratory tract remains fairly unknown, experiments using recombinant human TFFs (hTFF) show that they may serve several roles in maintaining

The Applications Of Fcm Technology In Three Different Diseases

2767 words - 11 pages sample, e.g. type and quality of the sample, and reagents used for the preparation. Also the instrument setup, calibration and potential bias in the interpretation are other limitations. Moreover most of the infectious diseases arise in poor developing counties which might not be apply to afford the cost of buying and maintaining FCM (Al-Mawali, Gillis and Lewis, 2009). This study discusses the possible applications of FCM in three different