“Streptococcus Pyogenes is a Gram-positive, nonmotile, nonsporeforming coccus that occurs in chains or in pairs of cells.” (Todar's Online Book of Bacteriology) In history, Streptococcus pyogenes got its ill repute as the cause of puerperal fever, a life-threatening disease that was seen in women after childbirth, until Ignaz Semmelweis exposed that it could be stopped by physicians just washing their hands before each vaginal examination.( Live Strong) S. pyogenes is one of the most frequent pathogens found in humans. An estimate of between 5-15% of humans port the bacterium S. pyogenes without any symptoms of illness. S. pyogenes can be usually found habituating in the respiratory tract ...view middle of the document...
Any contact with these exteriors can lead to spreading of the infection. S. pyogenes can be spread to cattle and then back to humans through raw milk and other food sources like salads and eggs which could also be contaminated. In this case though, cattle only acquire the bacteria and no the diseases or infections that come along with it. (Public Health Agency of Canada) Growth of S. pyogenes is stimulated by incubating in an atmosphere with augmented carbon dioxide. The incubation period is normally from 1 -3 days.
Virulence and Pathogenicity Factors:
Streptococcus pyogenes creates several virulence aspects that provide to its pathogenicity. A bacteria’s pathogenicity is its disease-causing abilities. The bacteria contain a capsule that helps allow it to camouflage itself from getting immersed by white blood cells. This process is known as phagocytosis. S. pyogenes also encloses proteins on its cell wall that permits it to stick to epithelial cells allowing it to produce an infection or disease. S. pyogenes also creates numerous enzymes that give the bacteria the aptitude to terminate tissue and spread. This bacterium also produces a extensive diversity of toxins that can produce minor symptoms. (Live Strong) Streptococcus pyogenes is responsible for many infections like sore throat. Some common symptoms of sore throat include fever and in flammed tonsils and lymph nodes. Other infections caused by this bacterium include scarlet fever, impetigo, and pneumonia. Less known infections that are also caused by S. Pyogenes are mastitis, sepsis, myositis, and meningitis. Every year Streptococcus pyogenes takes the lives or nearly 517,000 humans around the world. (Public Health Agency of Canada)
V. Treatment of Streptococcus pyogenes Infections:
Treatment of choice for S. Pyogenes infections is an antibiotic therapy of penicillin. Although penicillin proves to be very effective for these infections, macrolides are useful for patients who show allergic reactions to penicillin. (Pathology Outlines)
Clinical manifestations of S. Pyogenes varies within the...