Structure And Function Of The Spleen

1110 words - 4 pages

The spleen is a soft, spongy organ of the lymphatic system. It serves two general functions in adults:1.Fights infection. Acts as a giant lymph node, scanning erythrocytes, platelets and antigens. Lymphocytes produced in the spleen fight disease causing pathogens.2. Filters aged erythrocytes, platelets and blood-borne antigens.The spleen is the largest lymphatic mass in the body and lies intraperitoneally in the left upper quadrant. It sits on the left colic flexure1, in the left hyperchondriac region, between the stomach and diaphragm. Posteriorly, it is associated with the left 9th through 11th ribs, separated from them by the diaphragm. The diaphragmatic surface of the spleen is convexly curved to fit the concavity of the diaphragm. The posterior and inferior borders are rounded, whereas its anterior and superior borders are sharp and notched. The anterior aspect of the spleen contacts the posterior wall of the stomach and is connected to its curvature by the gastrosplenic ligament and to the kidney by the splenorenal ligament. The spleen usually measures 12cm by 7cm, which is roughly the size of a clenched fist. It weighs around 180-250g.1, 2The spleen is entirely surrounded by a capsule of dense connective tissue which, in turn is covered by a serous membrane visceral peritoneum (except the hilus). The visceral peritoneum is a collagenous membrane made of bands consisting of collagen and reticular fibres that provide support for two main splenic parenchyma structures, the white pulp and the red pulp. Long protrusions called trabeculae of the capsule extend interiorly into the organ. The stroma of the spleen consists of the capsule and its protruding trabeculae, reticular fibres, and fibroblasts. The white pulp and red pulp of the spleen form the parenchyma of the spleen. 1, 2The parenchyma of the spleen consisting of the white pulp and the red pulp.6The splenic artery enters the spleen through its hilus and supplies it with blood. The splenic artery branches into trabecular arteries which give rise to central arteries that leave the trabeculae and penetrate the parenchyma. The central arteries are in fact arterioles. Blood leaves the spleen through the splenic vein, which drains into a larger portal vein that supplies the liver. The efferent lymphatic vessels supplying the spleen pass through the hilus.1, 3The white pulp of the spleen contains the infection fighting lymphatic tissue. It is formed by small lymphocytes and macrophages arranged around the central arterioles. The periarteriolar sheath surrounding the central arterioles contains T lymphocytes, macrophages and antigen presenting cells. Surrounding the periarteriolar sheath is the marginal zone which contains B lymphocytes concentrated in lymphoid follicles, either primary 'unstimulated' follicles or secondary 'stimulated' follicles. The centre of the secondary follicles has a lower B cell density than the outer region of the secondary follicles as it contains larger and fewer B...

Find Another Essay On Structure And Function Of The Spleen

Notes on Membrane Structure and Function

1153 words - 5 pages *Membrane Structure and Function*Selective permeability- allows some substances to cross it more easily than others*Phospholipids are the most abundant lipids in membranes *An amphipathic molecule (has both hydrophilic and hydrophobic region), proteins too*Overton hypothesized that membranes are made of lipids*Langmuir made artificial membranes by adding phospholipids dissolved in benzene to water*Benzene evaporated, phospholipids

Form and Function of the Colosseum

1932 words - 8 pages Form and Function of the Colosseum Colosseum is an example of a building in which its form and function are inextricably linked. To prove this, let us take a look at some of the orders, the wall-like structure and the vaults of the Colosseum as part of its form and functions. With reference to the Illustration Book Colour Plate 19,28,72,75,76 and 78, and Block 2 The Colosseum Figure 6.1 and 6.2, the Colosseum

On the Function and Evolution of Sleep

1525 words - 6 pages On the Function and Evolution of Sleep If physiologists devoted the most research time to behaviors humans engaged in the most, we would probably have a full understanding of the biological purpose of sleep. After all, humans, with the exception of most college students, spend one third of their lives in a somnolent state. Despite its fundamental role in human and animal life, sleep is, even in an age when neuroscience has reduced many

The Nature and Function of Dreams

2675 words - 11 pages The Nature and Function of Dreams There is a state of consciousness in which one could be or experience anything imaginable. This state encompasses the ability to dream (1). The dream state is quite remarkable and incorporates infinite possibilities for the dreamer within each of us. Nietzsche (1844-1900), a German philosopher, points out that dreams were a puzzle since “the ages of rude beginning of culture” when “man believed that he was

What is the function of the Inspector in the play 'An Inspector Calls'? Consider what he represents, the way he affects structure and pace, his effect on the characters and his effect on the audience.

2012 words - 8 pages makes An Inspector Calls very much a morality play. The moral behind the storyline is that the people of Britain must now start to look out for each other. This is how the war was won and how the country will need to be, if it is to better itself.After considering what the function of the Inspector in the play is, I have come to the conclusion that the intention of the Inspector is to teach the characters and audience that it is time to change

The Function of Education

2862 words - 11 pages The Function of Education Education is an aspect of socialisation which involves the acquisition of knowledge and learning of skills. It shapes our beliefs and moral values through a systematic formal transmission. Education is said be an integral function of society, as it provides a contributory characteristic which helps to maintain and adapt society and it's values. Before the 1960's, education was taught

The Function of Punishment

2114 words - 8 pages reduce the harm caused by anti-social behaviour. Seen in this way punishment can be said to have a tripartite function - to deter, to reform, and to incapacitate. The extent to which any of these functions are successful is a matter of debate, as is the extent to which any one of these functions should take priority. Although the length of this essay precludes any real discussion on this subject, it would perhaps be as well

The Function of Government

1992 words - 8 pages Perhaps the most widely discussed topic, aside from celebrities and the weather, politics is also one of the most volatile. Its subjects are often involved in as much scandal as the former, and its geography changes as quickly as the latter. Politicians and their business are important because they make up the government. “What should government do?” and “How should government function?” are questions which will evoke drastically different

The Function of Pharmacokinetics

1057 words - 4 pages Pharmacokinetic has evolved over the years from being a graphic science to a systematic and is frequently used in the current clinical studies. Scientists are progressively being conscious and willing to collect relevant pharmacokinetic data by using the in vitro studies. In vitro studies will allow the safer and more predictable studies compared and results compare to in vivo studies. Interpretation of toxic side effects of all the

The Function of Soliloquies

1654 words - 7 pages Shakespeare relies heavily on soliloquies to help the reader understand Prince Hamlet. Hamlet is often speaking out loud when he is by himself. This lets the reader know what Hamlet is actually thinking despite what he is telling others around him (Mittelstaedt 126-27). The majority of the soliloquies are moments when Hamlet is overwhelmed by emotion at his situation and deeply upset. Hamlet’s sadness is what the play revolves around. In the

The structure and composition of the atmosphere

528 words - 2 pages The Earth is surrounded by a blanket of air, which we call the atmosphere. It reaches over 560 kilometers (348 miles) from the surface of the Earth, so we are only able to see what occurs fairly close to the ground. Life on Earth is supported by the atmosphere, solar energy, and our planet's magnetic fields. The atmosphere absorbs the energy from the Sun, recycles water and other chemicals, and works with the electrical and magnetic forces to

Similar Essays

Compare The Structure And Function Of The Xylem And Phloem

1486 words - 6 pages diffusion. Both stems and roots contain xylem vessels and phloem tubes. In a stem these are grouped into vascular bundles arranged in a ring. In a root these are arranged in the centre forming a structure called the stele.Xylem tissue has the dual functions of support and transport. It contains several different types of cells these are vessel elements, traceids, fibres and parenchyma cells. In contrast to this phloem tissue is living and comprises of

Structure And Function Essay

1261 words - 5 pages -binding activity (Levine, 1997; Cho et al., 1994). Also noted, the beta sheets in this domain are required to put the structural elements that interact with the DNA into place. Gene Function The structure of p53 is linked to its function. Mutations and missense deletions that alter this structure result in loss of functionality, as seen in many cancers. Losses or changes in p53 regulation/regulators (MDM2, p53 isoforms, amino acid resides 22

Evolution Of Organisms Shows The Development Of Structure To Function

1320 words - 5 pages Grouping of organisms according to the similar anatomy helps to understand their evolution and how those organisms have being developed over millions of years. Similarly, structures of organisms have developed over years to function better to survive on the earth. Even though some organisms are unicellular, while some are multicelliular, both types of organisms have got particular structure to function that helps to fulfill their needs. Thus

"Life Story", Which Is An Essay About The Race To Find The Structure And Function Of The Dna Macromolecule.

2428 words - 10 pages The hunt for where life comes from and what life consists of involved many different personalities, places, and events that came together to reveal an answer that had particularly become of interest in the years preceding the discovery, as much of the world tried to move away from death and closer to life. In 1953, James Watson and Francis Crick presented the structure and function of the nucleic acid DNA, the macromolecule found in living