Lupus has no precise meaning when used alone due to the various types, but it is a broad term for a chronic, progressive, skin disease. The types of lupus include: Lupus nephritis, Cutaneous lupus erythematosus, neuropsychiatric lupus, discoid lupus erythematosus, lupus pernio, lupus vulgaris, drug induced lupus erythematosus, and the most crucial systematic lupus erythematosus. The immune system is designated to attack foreign substances, but with lupus the immune system accidently attacks healthy cells and tissues damaging many parts of the body including: joints, the skin, kidneys, lungs, the heart, blood vessels, and the brain. Some people may only experience the skin symptoms which would indicate they have discoid lupus erythematosus, lupus pernio, lupus vulgaris, or cutaneous lupus erythematosus, but those that experience more problems are generally the systematic lupus erythematosus patients.
Systematic lupus erythematosus (SLE) is a chronic, multi-organ, auto-immune, inflammatory disease that is marked by exacerbation and remission periods. The term is derived from the characteristic of the malar (butterfly) rash, which is present in individuals with SLE. Only 8-15% of children are affected, so it predominantly occurs in adults, customarily in women of the childbearing age (20-40 years), with ratios of 9:1 for females and 15:1 for males. African-American women are three to four times more likely to develop SLE than Caucasian women, and those of Hispanic,Native American, Asian, and Afro-Caribbean decent have a higher incidence rate than those individuals of Caucasian race. This only applies for SLE, because those who encounter drug-induced lupus erythematosus (DILE) are more frequently Caucasian than African-American.
The difference between SLE and DILE is that DILE is caused by an overreaction to certain drugs including: Isoniazid (treats tuberculosis), Hydralazine (treats high blood pressure and prevents heart failure), Procainamide (treats irregular heart beats and overactive hearts), Chloropromazine (treats mental disorders, severe behavior disorders, severe hiccups, severe nausea/vomiting, and types of porphyria), Etanercept (Reduce Arthritis), Infliximab (treats Crohns disease), Methyldopa (treats high blood pressure), Minocycline (treats periodontal (gum) disease), Penicillamine (treats Wilson’s disease and arthritis), Quinidine (treats irregular heartbeat) , Sulfasalazine (treats arthritis and ulcerative colitis), Capoten (treats high blood pressure and congestive heart failure), and Anti-Seizure medications. It may be difficult to tell the difference between SLE and DILE, because they both can cause a butterfly rash, that extends over the cheeks and on the bridge of the nose and tends to worsen in sunlight. Although DILE is caused by medications it can be just as severe as SLE, but easier to treat; stop taking the medication and the symptoms will cease a few days to a week after the medication is stopped.