Thalidomide Essay

1767 words - 7 pages

# Since the mid to late 1950’s, Thalidomide has been a controversial drug. Since its introduction it has seen its highs and its lows. From devastating birth defects, to a treatment for some life threatening cancers, Thalidomide could be considered the Jeckel and Hyde of the pharmaceutical world. The question that the pharmaceutical world is asking itself now is weather the risk of the possible devastating birth defects that can happen is worth the possible life saving benefits that could be gained. Thalidomide has been the topic of debate since its uses as a treatment of certain cancers has been discovered.
# The drug was first introduced in the Europe. Thalidomide was prescribed to pregnant women to try and combat morning sickness. Thalidomide was also used as a sleep enhancer in other patients. It was not until 1961 that the drug was linked to the horrific malformations such as babies being born with flipper like limbs. It was also blamed for other birth defects effecting the eyes, ears, heart, genitals, kidneys, nervous system and digestive tract. The possibilities of subjecting more babies and their families to the effects of Thalidomide has many people upset about the idea that it may be coming back on the market. Just one dose of the drug to an unborn baby can cause dire effects. It takes a very small amount to cause any one of the serious problems listed above.
# Thalidomide was never produced or distributed in the United States, but a handful of “Thalidomide babies” were born to American families. Seven thousand to twelve thousand babies were born with defects due to Thalidomide in other parts of the world, including Europe and Canada. (Snider, 1995) As a result of the numerous problems with the drug, the FDA has created new guidelines for preclinical animal test to learn if a new compound causes birth defects before it ever enters humans. (Brown, 1997) Teratogenic, or birth defect causing, drugs are normally yanked off the market way before studies have been done to see if they have any other applications. The views of the pharmaceutical world are that nothing can be gained from a drug that causes life altering birth defects.
# Now, years later, Thalidomide has been given a chance to redeem itself. Early research has shown that the drug has been effective in treating a variety of ailments such as leprosy, tuberculoses, HIV, arthritis, and even cancer. Can there be a silver lining to the dark cloud of Thalidomide? Can such a devastating drug be used to perform miracles? That is what scientists are trying to find out.
# After seeing the risks involved with Thalidomide, from birth defects to possible nerve damage, you might be asking yourself why anyone would ever consider taking such a drug. The answer to that question is that they would consider the drug as a last hope, or to prolong or add comfort in their final days. When a person is given no hope for a cure, any possibility becomes what could be the light at the end of a very dark...

Find Another Essay On Thalidomide

College Application Essay on Chemistry

639 words - 3 pages petroleum and petrochemicals. Chemistry includes organic synthesis pathways which look at the yield’s of different reactions and predict the most efficient way of going from A to B. Chemistry discovers chemicals such as thalidomide which helped with pregnant women not having morning sickness but resulted in with the baby having missing limbs when they were born. Chemists have now found a new way to engineer thalidomide so precisely that it has the right

animals Essay

937 words - 4 pages amongst a human body and an animal body. The differences between human and animal bodies vary in many ways, such as, drugs treat animals differently than they would treat a human and the quantity of medication given to an animal exceeds any amount a human would consume. In 1960, animal testing gave invalid results for Thalidomide. Thalidomide is medication that was given to people for a sleeping aid and an antiemetic to reduce morning sickness

Why Animal Testing Isn't Always Representative of What Will Happen in Humans

1787 words - 8 pages , “we are not 70kg rats” (Perkel). Even when animals don’t have a reaction to a new medication, that doesn’t mean humans won’t. One good example of this, was the Thalidomide tragedy during the 1950’s and 60’s. The Thalidomide tragedy was a drug that was tested on animals, passed all the regulations, but had serious harmful effects on humans. “The drug had an estimated 10,000 birth defects and thousands of fetal deaths worldwide. The affected babies

Animal Experimentation

1661 words - 7 pages is using data from one species in order to predict the outcome in humans, puts people’s lives at risk. One example of this is Thalidomide. The National Center for Biotechnology (NCBI), Thalidomide is one of the greatest cases in history of a drug disaster tragedy caused by animal research. Thalidomide is a synthetic drug formerly used as a sedative and hypnotic but withdrawn from the market when found to cause abnormalities in developing fetuses

Animal Testing: Why Animal Testing Should Be Banned - Jakarta International College - Argumentative Essay

1745 words - 7 pages and a waste of time (PETA, 2011). This is because precious money, time, and resources that could have been spent on human-relevant research was wasted on years studying mice. Unfortunately to this day, we have not found a cure for cancer. There was a drug called thalidomide that was used in the late 1950s. It had several purposes which included relieving morning sickness for pregnant women. Sadly, it lead to serious birth defects and thousands

Silent Pain

1038 words - 4 pages results acquired from animal testing are mostly false because of the huge inequality amongst a human body and an animal body. The differences between human and animal bodies vary in many ways, such as, drugs treat animals differently than they would treat a human and the dosage of medication given to an animal exceeds any amount a human would consume. In 1960, animal testing gave invalid results for Thalidomide (Amin). Thalidomide is medication that

A Case Against Animal Testing

1186 words - 5 pages skin cells grown in test tubes. Computer models, virtual reconstructions of human molecular structures, can predict the toxic levels of substances without going to the extent of experimenting on animals. Drugs that pass animal tests are not necessarily safe. A sleeping pill called thalidomide caused 10,000 babies to be born with severe deformities. Thalidomide was tested on animals prior to its commercial release. Only the tests on

What are advantages and disadvantages of animal testing?

1251 words - 6 pages reason not to hurt people. However 92% of drugs that test good in animal fail during human trials according to Food and Drug administration. One of the brightest examples is thalidomide. This medicine has an awful reputation. Thalidomide is sedative for pregnant women. People, using it, could easily sleep all night. Its broad application led to that tens of thousands of children in the 1950th and 1960th years were born with deformities

Global Ethical Guidelines and Drug Use

1214 words - 5 pages caused the human race from reaching a conclusion in things such as cures for illnesses, advancement in technology, and discovering the future of the human race. Throughout history there have been many incidents in which these guidelines produced by ethical judgments have prevented gradual advancement in knowledge or have protected the harm that would otherwise be inflicted. The area of natural sciences I have chosen is the usage of Thalidomide

Discuss how notions of 'consumerism', 'pluralism' and 'modernity' are linked to the resurgence of CAM

1562 words - 6 pages rubella they were being vaccinated against that they were actually causing these illness and others. Since the 1960s and 1970s there has been a greater interest and demand for CAM therapies, as more and more information about the safety of bio-medical treatments, as was "highlighted by thalidomide" (Saks, 2005, Chapter 3, P74), which is another example of the doubts and questions raised can be seen in the administering of drugs such as thalidomide

Animal Rights

856 words - 3 pages , poisons cats, but does not affect horses". A well-known example of the misleading animal testing which harms human health is the thalidomide disaster. The box accompanying the thalidomide stated that after substantial animal tests, this drug was confirmed to be safe. However, birth defects were eventually caused if pregnant women had prescribed. This resulted in missing limbs in thousands of babies. In addition, there are many factors

Similar Essays

Side Effects Of The Drug Thalidomide

664 words - 3 pages Thalidomide was a popular drug used by many pregnant women in the 1950’s and 1960’s as a sedative. As stated by the Thalidomide Victims Association of Canada (2014),“The German drug company Chemie Grünenthal created Thalidomide to reduce the symptoms in pregnant patients experiencing morning sickness.”“After women taking thalidomide delivered their babies, it was evident that there was very severe and noticeable abnormalities.These birth defects

How To Kill A Joke Essay

1794 words - 8 pages first mother checks her watch and takes a pill from her purse. Popping it in her mouth, she smiles, and tells the other mothers “Vitamin A. Good for mom, good for baby!” and continues knitting. Then the second mother takes a pill out and swallows it, beaming, saying “Vitamin B, good for mom, good for baby.” She resumes her knitting. The third mother takes a pill, smiles, and says “Thalidomide… I can’t knit sleeves.” For some, the punchline to

Teratogens Essay

1000 words - 4 pages relates to developmental difficulties and heavy drinking also relates to a higher risk for miscarriage, stillbirth and low birth weight.Thalidomide was first introduced by "Chemie Gruenenthal" in West Germany in 1957 and was soon afterwards marketed under different names in 46 other countries (including the US, Canada, Japan, Saudi Arabia etc.). Thalidomide was used as a sleeping pill and to treat morning sickness in pregnant women.Its effects

The Cons Of Animal Experimentation Essay

943 words - 4 pages by studying the results. According to the “Animal Friends Croatia,” scientists had created “thalidomide”, a drug to help stop morning sickness for pregnant women. Even though it was tested on many species of animals before it was put on the market, it ended up causing thousands of birth defects (about 10,000) and fetal deaths around the world (“AFC-The Tragedy of Thalidomide”). Many problems like this have come out of animal tests that work on