This website uses cookies to ensure you have the best experience. Learn more

Use Of Anticougaulants In Prevention Of Ischemic Stroke And Pulmonary Embolism

2779 words - 11 pages

Use of Anticoagulants in Prevention of Ischemic Stroke and Pulmonary EmbolismSondus KahilEmily Isgur/ section 5AbstractThe Journal article "Rivaroxaban as an Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation" by Alexander GG Turpied discusses a new method for patients suffering from atrial fibrillation as a recommended form of treatment. Atrial fibrillation is the most prevalent form of cardiac arrhythmia in the developed world and is responsible for 15% of strokes that occur. Turpied summarizes this finding on the properties of Rivaroxban and found that it is a direct inhibitor of factor Xa furthermore concluding that is an appropriate method for anticoagulation therapy. According to produced clinical trials, Rivaroxban show significant reduction in bleeding when compared to Warfarin. The findings support recommendations to switch from vitamin K antagonist therapy to Rivaroxban.The journal article "The Pharmacology and Pharmacodynamics of Novel Oral Anticoagulants" by Tracy DeWald and Richard discuss and summarize their findings on new oral anticoagulants drugs to replace traditional vitamin K antagonist. This article revealed and summarized their findings on newer oral anticoagulants Dabigatran and Apixaban. Based on clinical trials they produce explanations as to why there are differences in bleeding outcomes of Vitamin K antagonists and Novel Oral anticoagulants. Less bleed may occur in the newer anticoagulants due to their direct inhibit activity of the clotting agent thrombin.IntroductionAnticoagulants have been a long time mandatory therapy in patients suffering from occurring ischemic stroke due to coronary syndrome and atrial fibrillation [1]. Anticoagulant drug therapy is also mandatory forms of drug therapy in order to significalty improve morbidity and mortality in patients suffering from such cases [2]. Anticoagulants are known as drugs that prevent the action of clotting factors or platelets within the blood [3]. Clotting factors in the blood are most commonly seen in patients suffering from recurring episodes of ischemic strike and pulmonary embolism; and such patients are often prescribed anticoagulants in as an effort to arrest further damage done by the clotting [4] furthermore to reduce strokes in patients anticoagulants such as vitamin K antagonists and Heparin are drugs that play a vital role in preventing stroke and pulmonary embolism[1] ischemic strokes occur when an artery leading to the brain is clogged or blocked, although ischemic stroke can be caused by several different diseases, the most common is atrial fibrillation. This occurs as a result of an irregular heartbeat. Such irregularity and abnormality of the heart valves lead to the formation of blood clots where they can be trapped in arteries leading to the brain [5]. Pulmonary embolism is a complication of venous thrombotic events that can be potentially fatal if not treated. Pulmonary embolism is characterized by a clog or blood clot forming in the...

Find Another Essay On use of anticougaulants in prevention of ischemic stroke and pulmonary embolism

Combination of Remote Ischemic Perconditioning and Local Postconditioning on Liver Ischemia-Reperfusion Injury

1821 words - 8 pages 1. Introduction Reperfusion following temporary tissue ischemia has been identified as an important mechanism contributing to tissue injury1. Furthermore, the clinical syndrome of ischemia and reperfusion (IR) is associated with deleterious consequences for several organs. This syndrome contributes to morbidity and mortality in a wide range of pathologies, including myocardial infarction, ischemic stroke, sleep apnea, circulatory arrest, and

Causes and Prevention of Suicide in Adolescents

1277 words - 6 pages among female victims. In the words of the San Francisco Child Abuse Prevention Center, “boys are at a higher risk and experience more severe abuse” (2011). Although the exact definition of sexual abuse is somewhat debated, most sources agree on a pretty basic definition: any type of sexual act that one person knowingly forces another, unwilling (or underaged) person to take part in. Unlike the victims of physical abuse who are mostly male, the vast

Overview of a Stroke

1159 words - 5 pages : ischemic stroke, hemorrhagic stroke, and transient ischemic stroke. Ischemic strokes occur due to an obstruction or clotting of a blood vessel or artery. There are two types of ischemic strokes: embolic and thrombotic strokes. An embolic stroke is when a blood clot or other substance forms in the body, travels through the blood stream, and eventually becomes lodged in a small blood vessel or artery supplying blood to the brain. A thrombotic stroke

Unconfirmed Diagnosis of Stroke

2130 words - 9 pages Guidelines Network 2010, Management of patients with stroke: Rehabilitation, prevention and management of complications, and discharge planning A national clinical guideline viewed 27th April 2014 pp. 1-101. Shaker, R & Geenen, JE 2011 'Management of Dysphagia in stroke patients', Gastroenterology & hepatology, vol. 7, no. 5, pp. 308-332. Statewide Stroke Clinical Network 2012, Government of South Australia

Role of Exercise in the Prevention and Management of Osteoporosis

3334 words - 13 pages osteoporosis prevention. Initiating lifestyle changes in childhood and adolescence could decrease the incidence of osteoporosis. This module includes age specific information about osteoporosis to women across the life span. It also provides updates on recent findings related to prevention, detection and the treatment of osteoporosis. 4- Description of the participants for the hypothetical project and why they are selected. One of the major

Prevention of Suicide in Adolescents

1632 words - 7 pages The community impact, which includes national, state, and community level, is crucial for suicide prevention in adolescents. By having the community involved, it allows a more effective prevention plan, along with measures on how to properly handle the situation more efficiently. The U.S. Department of Health and Human Services (HHS) Office of the Surgeon General and National Action Alliance for Suicide, revised the National Strategy for Suicide

Determinants of quality of life in stroke survivors after 6 months, from comprehensive stroke unit in Spain. A longitudinal study

886 words - 4 pages Our results highlight the negative consequences of stroke on both the physical and mental dimensions of HRQoL as assessed using the SF-12. Moreover, we must emphasize that quality of life is lower in stroke survivors than in the general population, regardless of type of stroke (Haley et al., 2011; Monteagudo-Piqueras, et al., 2007; Schmidt et al., 2012; Vilagut et al., 2008). Most of the studies we reviewed evaluate HRQoL beginning at the time

The Effects Of A Stroke

2147 words - 9 pages from the disease and how strokes affect victims.Two kinds of strokes are differentiated in the medical field. An ischemic stroke is a blockage of blood in the brain or neck. According to "Stroke types: Hemorrhagic versus Ischemic," "In most ischemic strokes a blood clot finishes the job by totally obstructing the flow of blood through the vessel. When a blood clot forms somewhere else (for instance, in the heart) and then travels through the blood

Theory and Construction of a Care Plan for Stroke Rehabilitation

3962 words - 16 pages prevent significant discomfort. The use of a catheter initially is of great help during the initial stages of rehabilitation on admission Mary was incontinent of faeces and already catheterised. Since the stroke Mary seem to have no control over her elimination and was even unaware that she had been. So she was placed on a fluid balance chart to record any abnormalities in her urinary output and a stool chart to try to establish a pattern, to lessen

Research on Management and Prevention of Stress in the Workplace

1651 words - 7 pages Journal Of Occupational Safety And Ergonomics, 2002, says stress prevention in organizations is aimed at preventing individual and organizational distress in three stages: primary prevention (stressor-directed prevention), secondary prevention (response-directed prevention), and tertiary prevention claim that while primary prevention is focused on adapting the environment to fit the individual, secondary prevention should be concerned with the

Auditor's Role in Prevention and Detection of Payroll Fraud

2114 words - 8 pages implemented. Usually, employees have the tendency to deviate from the standard policies and procedures set by management, or make use of shortcuts Internal auditors are necessary in the organization to ensure that policies and business processes are effectively implemented. They are vital in achieving organizational goals and used by management to safeguard the company’s resources, to evaluate the accuracy of financial reporting, and to

Similar Essays

The Use Of Vitamin B12 In Stroke Prevention And Post Stroke Recovery

2177 words - 9 pages of the 120 participants. While this study was significantly shorter than the VITACOG the results were similar using 500 μg of Vitamin B12. A significant improvement was seen in not only the Hcy levels but also in cognitive impairment (P<0.01). With the known association between Hcy and stroke risk these decreases are clinically significant, providing a mechanism for stroke prevention in high risk populations. It is essential that Vitamin B12

Is Clopidogrel Effective In The Prevention Of Secondary Stroke

727 words - 3 pages Is Clopidogrel effective in the prevention of secondary stroke in a 65 year-old male who recently had a stroke? Ischemic Stroke is caused due to a blood clot in an area of the brain, leading to loss of neural function if last for more than 24 hours. In the United States, ischemic stroke affects 2.7% of men and 2.5% of women of age range 18 years and older. In addition, it has reported that annually about 610,000 and 185,000 of new strokes and

Cannabinoid Receptor Type 1 Agonist, Acea, Improves Motor Recovery And Protects Neurons In Ischemic Stroke In Mice

2774 words - 12 pages . Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.J Neurosci. 25(8):1904-1913. Reynolds E.S., 1963. The use of lead citrate at high pH as an electronopaque stain in electron microscopy. J Cell Biol. 17:208–212. Schallert T., Fleming S., Leasure J., Tillerson J., Bland S., 2000. CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke

Pathology And Treatment Of Pulmonary Arterial Hypertension

2205 words - 9 pages The pulmonary vasculature contains arteries and arterioles, which branch in the lungs to create a dense capillary bed to provide blood flow. The pulmonary capillary bed is a high-volume, low-pressure, low-resistance system that delivers blood to and from the lungs via the arterial and venous circulation systems. The right ventricle of the heart is responsible for pumping blood to the pulmonary artery and to the lungs so it can be oxygenated